Primary malignant glomus tumors of the thyroid gland: A case report
Malignant glomus tumors are rare mesenchymal tumors arising from the smooth muscle cells of the glomus body. Primary malignant glomus tumors of the thyroid are atypical. An 80-year-old man presented with a right thyroid tumor on computed tomography (CT) and was suspected of having multiple bilateral...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Acta Oto-Laryngologica Case Reports |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/23772484.2024.2370585 |
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| author | Shinya Morita Nobuya Monden Jiro Aoi Shiori Aibara Hiroaki Tahara Norihiro Teramoto |
| author_facet | Shinya Morita Nobuya Monden Jiro Aoi Shiori Aibara Hiroaki Tahara Norihiro Teramoto |
| author_sort | Shinya Morita |
| collection | DOAJ |
| description | Malignant glomus tumors are rare mesenchymal tumors arising from the smooth muscle cells of the glomus body. Primary malignant glomus tumors of the thyroid are atypical. An 80-year-old man presented with a right thyroid tumor on computed tomography (CT) and was suspected of having multiple bilateral pulmonary metastases. The right lobe of the thyroid gland was accompanied by a low-density tumor and calcification inside, and infiltration into the trachea and cervical esophagus was deduced. Core needle biopsy (CNB) confirmed that round to polygonal atypical cells were growing in sheet form around the vascular endothelial cells. Immunohistochemistry results were positive for vimentin and smooth muscle actin (SMA) but negative for pan-cytokeratin and S-100 protein. Chemotherapy with doxorubicin was initiated. However, due to the progression of the disease, doxorubicin was replaced with pazopanib. His condition deteriorated further, and he died 3 months after the treatment. Overall, this disease has a poor prognosis. |
| format | Article |
| id | doaj-art-2d454d9d95e647769c63b34d899ff358 |
| institution | OA Journals |
| issn | 2377-2484 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Acta Oto-Laryngologica Case Reports |
| spelling | doaj-art-2d454d9d95e647769c63b34d899ff3582025-08-20T01:56:52ZengTaylor & Francis GroupActa Oto-Laryngologica Case Reports2377-24842024-12-019111411910.1080/23772484.2024.2370585Primary malignant glomus tumors of the thyroid gland: A case reportShinya Morita0Nobuya Monden1Jiro Aoi2Shiori Aibara3Hiroaki Tahara4Norihiro Teramoto5Department of Head and Neck Surgery, Shizuoka Cancer Center Hospital, Shizuoka, JapanDepartment of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, JapanDepartment of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, JapanDepartment of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, JapanDepartment of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, JapanDepartment of Pathology, National Hospital Organization Shikoku Cancer Center, Matsuyama, JapanMalignant glomus tumors are rare mesenchymal tumors arising from the smooth muscle cells of the glomus body. Primary malignant glomus tumors of the thyroid are atypical. An 80-year-old man presented with a right thyroid tumor on computed tomography (CT) and was suspected of having multiple bilateral pulmonary metastases. The right lobe of the thyroid gland was accompanied by a low-density tumor and calcification inside, and infiltration into the trachea and cervical esophagus was deduced. Core needle biopsy (CNB) confirmed that round to polygonal atypical cells were growing in sheet form around the vascular endothelial cells. Immunohistochemistry results were positive for vimentin and smooth muscle actin (SMA) but negative for pan-cytokeratin and S-100 protein. Chemotherapy with doxorubicin was initiated. However, due to the progression of the disease, doxorubicin was replaced with pazopanib. His condition deteriorated further, and he died 3 months after the treatment. Overall, this disease has a poor prognosis.https://www.tandfonline.com/doi/10.1080/23772484.2024.2370585Malignant glomus tumorthyroidhead and neckhead and neck tumors |
| spellingShingle | Shinya Morita Nobuya Monden Jiro Aoi Shiori Aibara Hiroaki Tahara Norihiro Teramoto Primary malignant glomus tumors of the thyroid gland: A case report Acta Oto-Laryngologica Case Reports Malignant glomus tumor thyroid head and neck head and neck tumors |
| title | Primary malignant glomus tumors of the thyroid gland: A case report |
| title_full | Primary malignant glomus tumors of the thyroid gland: A case report |
| title_fullStr | Primary malignant glomus tumors of the thyroid gland: A case report |
| title_full_unstemmed | Primary malignant glomus tumors of the thyroid gland: A case report |
| title_short | Primary malignant glomus tumors of the thyroid gland: A case report |
| title_sort | primary malignant glomus tumors of the thyroid gland a case report |
| topic | Malignant glomus tumor thyroid head and neck head and neck tumors |
| url | https://www.tandfonline.com/doi/10.1080/23772484.2024.2370585 |
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