Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system

The potential complimentary role of various molecular imaging modalities [fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), ultrasound (US)-elastography, and  diffusion weighted imaging-magnetic resonance imaging (DWI-MRI)] in characterizing thyroid nodules, which hav...

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Main Authors: Sandip Basu, Abhishek Mahajan, Supreeta Arya
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2016-04-01
Series:World Journal of Nuclear Medicine
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.176883
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author Sandip Basu
Abhishek Mahajan
Supreeta Arya
author_facet Sandip Basu
Abhishek Mahajan
Supreeta Arya
author_sort Sandip Basu
collection DOAJ
description The potential complimentary role of various molecular imaging modalities [fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), ultrasound (US)-elastography, and  diffusion weighted imaging-magnetic resonance imaging (DWI-MRI)] in characterizing thyroid nodules, which have been designated as "intermediate risk category" on the  Bethesda thyroid cytopathology reporting system (BTCRS), is illustrated in this communication. The clinical cases described (category III thyroid nodules on BTCRS) show the imaging features and  the final diagnostic impressions rendered by the interpreting physicians with the modalities that have been independently compared in a tabular format at the end; of particular note is the high negative predictive value of these (specifically FDG-PET/CT), which could aid in enhancing the diagnostic confidence in the reported "intermediate risk category" thyroid nodules, a "gray zone" from the patient management viewpoint.
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spelling doaj-art-2d422a53fc704a76ba9c1a91ec99338d2025-08-20T02:01:39ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122016-04-01150213013310.4103/1450-1147.176883Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting systemSandip Basu0Abhishek Mahajan1Supreeta Arya2Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, IndiaRadiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, IndiaRadiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, IndiaThe potential complimentary role of various molecular imaging modalities [fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), ultrasound (US)-elastography, and  diffusion weighted imaging-magnetic resonance imaging (DWI-MRI)] in characterizing thyroid nodules, which have been designated as "intermediate risk category" on the  Bethesda thyroid cytopathology reporting system (BTCRS), is illustrated in this communication. The clinical cases described (category III thyroid nodules on BTCRS) show the imaging features and  the final diagnostic impressions rendered by the interpreting physicians with the modalities that have been independently compared in a tabular format at the end; of particular note is the high negative predictive value of these (specifically FDG-PET/CT), which could aid in enhancing the diagnostic confidence in the reported "intermediate risk category" thyroid nodules, a "gray zone" from the patient management viewpoint.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.176883diffusion weighted imaging-magnetic resonance imaging (dwi-mri)fine-needle aspiration cytology (fnac)fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 f-fdg-pet/ct)ultrasound (us)-elastography
spellingShingle Sandip Basu
Abhishek Mahajan
Supreeta Arya
Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
World Journal of Nuclear Medicine
diffusion weighted imaging-magnetic resonance imaging (dwi-mri)
fine-needle aspiration cytology (fnac)
fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 f-fdg-pet/ct)
ultrasound (us)-elastography
title Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
title_full Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
title_fullStr Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
title_full_unstemmed Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
title_short Multimodality molecular imaging (FDG-PET/CT, US elastography, and DWI-MRI) as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
title_sort multimodality molecular imaging fdg pet ct us elastography and dwi mri as complimentary adjunct for enhancing diagnostic confidence in reported intermediate risk category thyroid nodules on bethesda thyroid cytopathology reporting system
topic diffusion weighted imaging-magnetic resonance imaging (dwi-mri)
fine-needle aspiration cytology (fnac)
fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 f-fdg-pet/ct)
ultrasound (us)-elastography
url http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.176883
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AT abhishekmahajan multimodalitymolecularimagingfdgpetctuselastographyanddwimriascomplimentaryadjunctforenhancingdiagnosticconfidenceinreportedintermediateriskcategorythyroidnodulesonbethesdathyroidcytopathologyreportingsystem
AT supreetaarya multimodalitymolecularimagingfdgpetctuselastographyanddwimriascomplimentaryadjunctforenhancingdiagnosticconfidenceinreportedintermediateriskcategorythyroidnodulesonbethesdathyroidcytopathologyreportingsystem