Jiedutongluotiaogan Formula Improves Pancreatic Dysfunction in db/db Mice through Modulating the Gut Microbiota-Short Chain Fatty Acids-NLR Family, Pyrin Domain–Containing Protein 3 Inflammasome

Jiedutongluotiaogan Formula Improves Pancreatic Dysfunction in db/db Mice through Modulating the Gut Microbiota-Short Chain Fatty Acids-NLR Family, Pyrin Domain–Containing Protein 3 Inflammasome

Objective: Disturbance of gut microbiota plays an essential role in metabolic diseases, such as diabetes. Jiedutongluotiaogan formula (JTTF) was designed to meliorate the symptoms of type 2 diabetes. Materials and Methods: In this study, we used a db/db mouse model to determine the possible relation...

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Bibliographic Details
Main Authors: Jin-Li Luo, Wen-Qi Jin, Li Wang, Qi Zhang, Yu Wang, Cui Wu, Yue Qu, Yu-Ting Peng, Li-Wei Sun, Chun-Li Piao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:World Journal of Traditional Chinese Medicine
Subjects:
diabetes
gut microbiota
jiedutongluotiaogan formula
nlr family
pyrin domain–containing protein 3
short-chain fatty acids
Online Access:https://journals.lww.com/10.4103/wjtcm.wjtcm_99_24
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