FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Abstract Small extracellular vesicles (sEVs) contain abundant circular RNAs (circRNAs) and are involved in cellular processes, particularly hypoxia. However, the process that packaging of circRNAs into neuronal sEVs under hypoxia is unclear. This study revealed the spatial mechanism of the Fused in...

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Bibliographic Details
Main Authors: Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
circular RNAs (circRNAs)
Fused‐in‐Sarcoma protein (FUS)
Hypoxia, Small extracellular vesicles (sEVs)
Stress granules
Online Access:https://doi.org/10.1002/advs.202404822
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