Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus
Mammalian target of rapamycin inhibitor everolimus is a novel agent used in endocrine therapy resistant hormone receptor positive metastatic breast cancer. Its use has been associated with clinically significant improvement in the otherwise dismal outcomes of this subset of patients. Rash is a commo...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2016-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
| Subjects: | |
| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2016;volume=37;issue=2;spage=116;epage=118;aulast=Arora |
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| _version_ | 1850238060700106752 |
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| author | Shalabh Arora Rajendra Akhil Raju Titus Chacko Renu George |
| author_facet | Shalabh Arora Rajendra Akhil Raju Titus Chacko Renu George |
| author_sort | Shalabh Arora |
| collection | DOAJ |
| description | Mammalian target of rapamycin inhibitor everolimus is a novel agent used in endocrine therapy resistant hormone receptor positive metastatic breast cancer. Its use has been associated with clinically significant improvement in the otherwise dismal outcomes of this subset of patients. Rash is a common adverse effect associated with everolimus. However, Hand-foot syndrome is an uncommon toxicity with the use of this drug. We report a case of Grade 3 hand-foot syndrome following institution of everolimus therapy and describe its successful management. |
| format | Article |
| id | doaj-art-2d30f575a0be42dbb3068c573b5f7e83 |
| institution | OA Journals |
| issn | 0971-5851 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-2d30f575a0be42dbb3068c573b5f7e832025-08-20T02:01:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512016-01-0137211611810.4103/0971-5851.180143Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimusShalabh AroraRajendra AkhilRaju Titus ChackoRenu GeorgeMammalian target of rapamycin inhibitor everolimus is a novel agent used in endocrine therapy resistant hormone receptor positive metastatic breast cancer. Its use has been associated with clinically significant improvement in the otherwise dismal outcomes of this subset of patients. Rash is a common adverse effect associated with everolimus. However, Hand-foot syndrome is an uncommon toxicity with the use of this drug. We report a case of Grade 3 hand-foot syndrome following institution of everolimus therapy and describe its successful management.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2016;volume=37;issue=2;spage=116;epage=118;aulast=AroraBreast cancer, everolimus, hand-foot syndrome, mammalian target of rapamycin inhibitors, palmar-plantar erythrodysesthesia |
| spellingShingle | Shalabh Arora Rajendra Akhil Raju Titus Chacko Renu George Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus Indian Journal of Medical and Paediatric Oncology Breast cancer, everolimus, hand-foot syndrome, mammalian target of rapamycin inhibitors, palmar-plantar erythrodysesthesia |
| title | Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus |
| title_full | Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus |
| title_fullStr | Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus |
| title_full_unstemmed | Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus |
| title_short | Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus |
| title_sort | palmar plantar erythrodysesthesia an uncommon adverse effect of everolimus |
| topic | Breast cancer, everolimus, hand-foot syndrome, mammalian target of rapamycin inhibitors, palmar-plantar erythrodysesthesia |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2016;volume=37;issue=2;spage=116;epage=118;aulast=Arora |
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