Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules

Objective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroide...

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Main Authors: Stella Bernardi, Chiara Dobrinja, Bruno Fabris, Gabriele Bazzocchi, Nicoletta Sabato, Veronica Ulcigrai, Massimo Giacca, Enrica Barro, Nicolò De Manzini, Fulvio Stacul
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/934595
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author Stella Bernardi
Chiara Dobrinja
Bruno Fabris
Gabriele Bazzocchi
Nicoletta Sabato
Veronica Ulcigrai
Massimo Giacca
Enrica Barro
Nicolò De Manzini
Fulvio Stacul
author_facet Stella Bernardi
Chiara Dobrinja
Bruno Fabris
Gabriele Bazzocchi
Nicoletta Sabato
Veronica Ulcigrai
Massimo Giacca
Enrica Barro
Nicolò De Manzini
Fulvio Stacul
author_sort Stella Bernardi
collection DOAJ
description Objective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroidectomy for the treatment of benign thyroid nodules. Design and Methods. 37 patients who underwent RFA were retrospectively compared to 74 patients surgically treated, either in a standard inpatient or in a short-stay surgical regimen. Efficacy, tolerability, and costs were compared. The contribution of final pathology was also taken into account. Results. RFA reduced nodular volume by 70% after 12 months and it was an effective method for treating nodule-related clinical problems, but it was not as effective as surgery for the treatment of hot nodules. RFA and surgery were both safe, although RFA had less complications and pain was rare. RFA costed €1,661.50, surgery costed €4,556.30, and short-stay surgery costed €4,139.40 per patient. RFA, however, did not allow for any pathologic analysis of the nodules, which, in 6 patients who had undergone surgery (8%), revealed that the nodules harboured malignant cells. Conclusions. RFA might transform our approach to benign thyroid nodules.
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institution Kabale University
issn 1687-8337
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series International Journal of Endocrinology
spelling doaj-art-2d280602c1fa4bb2a5808add6ec74eff2025-02-03T07:24:34ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/934595934595Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid NodulesStella Bernardi0Chiara Dobrinja1Bruno Fabris2Gabriele Bazzocchi3Nicoletta Sabato4Veronica Ulcigrai5Massimo Giacca6Enrica Barro7Nicolò De Manzini8Fulvio Stacul9UCO Medicina Clinica, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Chirurgia Generale, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Medicina Clinica, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalySC Radiologia, Azienda Ospedaliero-Universitaria di Trieste, Maggiore Hospital, Piazza dell’Ospitale, 34100 Trieste, ItalyUCO Medicina Clinica, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Radiologia, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Chirurgia Generale, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Medicina Clinica, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalyUCO Chirurgia Generale, Azienda Ospedaliero-Universitaria di Trieste, Cattinara Hospital, Strada di Fiume, 34100 Trieste, ItalySC Radiologia, Azienda Ospedaliero-Universitaria di Trieste, Maggiore Hospital, Piazza dell’Ospitale, 34100 Trieste, ItalyObjective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroidectomy for the treatment of benign thyroid nodules. Design and Methods. 37 patients who underwent RFA were retrospectively compared to 74 patients surgically treated, either in a standard inpatient or in a short-stay surgical regimen. Efficacy, tolerability, and costs were compared. The contribution of final pathology was also taken into account. Results. RFA reduced nodular volume by 70% after 12 months and it was an effective method for treating nodule-related clinical problems, but it was not as effective as surgery for the treatment of hot nodules. RFA and surgery were both safe, although RFA had less complications and pain was rare. RFA costed €1,661.50, surgery costed €4,556.30, and short-stay surgery costed €4,139.40 per patient. RFA, however, did not allow for any pathologic analysis of the nodules, which, in 6 patients who had undergone surgery (8%), revealed that the nodules harboured malignant cells. Conclusions. RFA might transform our approach to benign thyroid nodules.http://dx.doi.org/10.1155/2014/934595
spellingShingle Stella Bernardi
Chiara Dobrinja
Bruno Fabris
Gabriele Bazzocchi
Nicoletta Sabato
Veronica Ulcigrai
Massimo Giacca
Enrica Barro
Nicolò De Manzini
Fulvio Stacul
Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
International Journal of Endocrinology
title Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
title_full Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
title_fullStr Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
title_full_unstemmed Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
title_short Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
title_sort radiofrequency ablation compared to surgery for the treatment of benign thyroid nodules
url http://dx.doi.org/10.1155/2014/934595
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