scRDEN: single-cell dynamic gene rank differential expression network and robust trajectory inference

Abstract The remarkable advancement of single-cell RNA sequencing (scRNA-seq) technology has empowered researchers to probe gene expression at the single-cell level with unprecedented precision. To gain a profound understanding of the heterogeneity inherent in cell fate determination, a central chal...

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Bibliographic Details
Main Authors: Han Zhang, Wei Zhang, Xiaoying Zheng, Yuanyuan Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-01969-1
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