Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury

Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury

Objective(s): Ellagic acid (EA) is a natural polyphenol with anti-cancer, anti-oxidant, anti-inflammatory, antibacterial, and other effects. However, the role of EA in cerebral ischemia/reperfusion injury (CIRI) remains unclear. This study aims to investigate the neuroprotective effects of EA in CIR...

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Bibliographic Details
Main Authors: Ling Hu, Xiaoqiong Wei, Guofu Shen, Xiaohuan Huang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cerebral ischemia/reperfusion injury
ellagic acid
inflammation
nlrp6 inflammasome
pyroptosis
Online Access:https://ijbms.mums.ac.ir/article_25031_ae4c6740428568aeb07d87ea54ce5d3a.pdf
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