Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images
Background/Aims: Cholecystectomy for gallbladder (GB) polyps is performed primarily based on preoperative images. This study examined the accuracy of surgical indications commonly used in clinical practice for detecting neoplastic polyps and investigated further clues for predicting neoplastic polyp...
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Jin Publishing & Printing Co.
2025-01-01
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| Series: | The Korean Journal of Gastroenterology |
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| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=6080&vmd=Full |
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| author | Ik Hyun Jo Chang Nyol Paik Hong Geun Ahn Dong Do You Jae Hyun Han Hyun A Kim |
| author_facet | Ik Hyun Jo Chang Nyol Paik Hong Geun Ahn Dong Do You Jae Hyun Han Hyun A Kim |
| author_sort | Ik Hyun Jo |
| collection | DOAJ |
| description | Background/Aims: Cholecystectomy for gallbladder (GB) polyps is performed primarily based on preoperative images. This study examined the accuracy of surgical indications commonly used in clinical practice for detecting neoplastic polyps and investigated further clues for predicting neoplastic polyps.
Methods: This retrospective study included 385 patients who underwent a cholecystectomy for GB polyps. The predictive performances of seven surgical indications were compared by fitting the receiver operating characteristic curves. Logistic regression analysis was used to identify the candidate variables associated with predicting neoplastic polyps.
Results: Neoplastic polyps were identified in 18.9% (n=62) of the 385 patients assessed. The neoplastic group contained more females than males, larger polyps, more frequent solitary lesions, and lower platelet counts than the non-neoplastic group. Current surgical indications revealed an unsatisfactory prediction for neoplastic polyps. The optimal cutoff polyp size for neoplastic polyps by ultrasound (US) was larger than by computed tomography (CT) (12 mm vs. 10 mm). The proportion of pathologic neoplastic polyps was higher when both US and CT images were used than that predicted using a single test. Logistic regression analysis revealed larger polyps, increasing age, female sex, and lower platelet count to be associated with neoplastic polyps.
Conclusions: The current indications for cholecystectomy in GB polyps have a low predictive value for neoplastic lesions that can lead to overtreatment. Combining the polyp size from US and CT images may reduce unnecessary surgery. In addition, knowledge of the patient's age, sex, and platelet count could help make more selective surgical decisions for neoplastic polyps. |
| format | Article |
| id | doaj-art-2d10e06ccd374f2c8e3ebcd9506514a7 |
| institution | Kabale University |
| issn | 1598-9992 2233-6869 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj-art-2d10e06ccd374f2c8e3ebcd9506514a72025-02-07T06:20:44ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692025-01-01851526310.4166/kjg.2024.130Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative ImagesIk Hyun Jo0Chang Nyol Paik1https://orcid.org/0000-0002-3470-6904Hong Geun Ahn2Dong Do You3Jae Hyun Han4Hyun A Kim5Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaBackground/Aims: Cholecystectomy for gallbladder (GB) polyps is performed primarily based on preoperative images. This study examined the accuracy of surgical indications commonly used in clinical practice for detecting neoplastic polyps and investigated further clues for predicting neoplastic polyps. Methods: This retrospective study included 385 patients who underwent a cholecystectomy for GB polyps. The predictive performances of seven surgical indications were compared by fitting the receiver operating characteristic curves. Logistic regression analysis was used to identify the candidate variables associated with predicting neoplastic polyps. Results: Neoplastic polyps were identified in 18.9% (n=62) of the 385 patients assessed. The neoplastic group contained more females than males, larger polyps, more frequent solitary lesions, and lower platelet counts than the non-neoplastic group. Current surgical indications revealed an unsatisfactory prediction for neoplastic polyps. The optimal cutoff polyp size for neoplastic polyps by ultrasound (US) was larger than by computed tomography (CT) (12 mm vs. 10 mm). The proportion of pathologic neoplastic polyps was higher when both US and CT images were used than that predicted using a single test. Logistic regression analysis revealed larger polyps, increasing age, female sex, and lower platelet count to be associated with neoplastic polyps. Conclusions: The current indications for cholecystectomy in GB polyps have a low predictive value for neoplastic lesions that can lead to overtreatment. Combining the polyp size from US and CT images may reduce unnecessary surgery. In addition, knowledge of the patient's age, sex, and platelet count could help make more selective surgical decisions for neoplastic polyps.https://www.kjg.or.kr/journal/view.html?uid=6080&vmd=Fullgallbladder neoplasmspolypscholecystectomydiagnostic imagingpredictive value of tests |
| spellingShingle | Ik Hyun Jo Chang Nyol Paik Hong Geun Ahn Dong Do You Jae Hyun Han Hyun A Kim Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images The Korean Journal of Gastroenterology gallbladder neoplasms polyps cholecystectomy diagnostic imaging predictive value of tests |
| title | Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images |
| title_full | Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images |
| title_fullStr | Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images |
| title_full_unstemmed | Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images |
| title_short | Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images |
| title_sort | predicting neoplastic gallbladder polyps the role of current surgical indications and preoperative images |
| topic | gallbladder neoplasms polyps cholecystectomy diagnostic imaging predictive value of tests |
| url | https://www.kjg.or.kr/journal/view.html?uid=6080&vmd=Full |
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