Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China
Objective. This study aimed to explore the incidence of stroke and stroke subtypes among patients with type 2 diabetes mellitus (T2DM) based on the long-term surveillance data in Zhejiang, China, during 2007 to 2013. Materials and Methods. During January 1, 2007, and December 31, 2013, a total of 32...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/6380620 |
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| author | Lihua Guo Min Yu Jieming Zhong Haibin Wu Jin Pan Weiwei Gong Meng Wang Fangrong Fei Ruying Hu |
| author_facet | Lihua Guo Min Yu Jieming Zhong Haibin Wu Jin Pan Weiwei Gong Meng Wang Fangrong Fei Ruying Hu |
| author_sort | Lihua Guo |
| collection | DOAJ |
| description | Objective. This study aimed to explore the incidence of stroke and stroke subtypes among patients with type 2 diabetes mellitus (T2DM) based on the long-term surveillance data in Zhejiang, China, during 2007 to 2013. Materials and Methods. During January 1, 2007, and December 31, 2013, a total of 327,268 T2DM and 307,984 stroke patients were registered on Diabetes and Stroke Surveillance System, respectively. Stroke subtypes were classified according to standard definitions of subarachnoid hemorrhage, intracerebral hemorrhage, and ischemic stroke. The incidence of stroke and stroke subtypes was calculated by standardized incidence ratio (SIRs) with 95% confidence intervals (CIs) compared with general population. Results. The incidence of stroke and stroke subtypes among patients with T2DM was significantly higher than in general population. Stroke risk was found significantly increased with an SIR of 3.87 (95% CI 3.76–3.99) and 3.38 (95% CI 3.27–3.48) in females and males, respectively. The excess risk of stroke was mainly attributable to the significantly higher risk of cerebral infarctions with the risk for T2DM being four times that for general population. Conclusions. The relationship between stroke and T2DM was strong, especially in female. The incidence of stroke and stroke subtypes among patients with T2DM was up to 3-fold higher than in general population in Zhejiang province, especially the subtype of cerebral infarctions. |
| format | Article |
| id | doaj-art-2d0d969e30da45f7a59d4fa77213ba9c |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-2d0d969e30da45f7a59d4fa77213ba9c2025-02-03T00:59:48ZengWileyInternational Journal of Endocrinology1687-83371687-83452016-01-01201610.1155/2016/63806206380620Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in ChinaLihua Guo0Min Yu1Jieming Zhong2Haibin Wu3Jin Pan4Weiwei Gong5Meng Wang6Fangrong Fei7Ruying Hu8Zhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou 310051, ChinaObjective. This study aimed to explore the incidence of stroke and stroke subtypes among patients with type 2 diabetes mellitus (T2DM) based on the long-term surveillance data in Zhejiang, China, during 2007 to 2013. Materials and Methods. During January 1, 2007, and December 31, 2013, a total of 327,268 T2DM and 307,984 stroke patients were registered on Diabetes and Stroke Surveillance System, respectively. Stroke subtypes were classified according to standard definitions of subarachnoid hemorrhage, intracerebral hemorrhage, and ischemic stroke. The incidence of stroke and stroke subtypes was calculated by standardized incidence ratio (SIRs) with 95% confidence intervals (CIs) compared with general population. Results. The incidence of stroke and stroke subtypes among patients with T2DM was significantly higher than in general population. Stroke risk was found significantly increased with an SIR of 3.87 (95% CI 3.76–3.99) and 3.38 (95% CI 3.27–3.48) in females and males, respectively. The excess risk of stroke was mainly attributable to the significantly higher risk of cerebral infarctions with the risk for T2DM being four times that for general population. Conclusions. The relationship between stroke and T2DM was strong, especially in female. The incidence of stroke and stroke subtypes among patients with T2DM was up to 3-fold higher than in general population in Zhejiang province, especially the subtype of cerebral infarctions.http://dx.doi.org/10.1155/2016/6380620 |
| spellingShingle | Lihua Guo Min Yu Jieming Zhong Haibin Wu Jin Pan Weiwei Gong Meng Wang Fangrong Fei Ruying Hu Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China International Journal of Endocrinology |
| title | Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China |
| title_full | Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China |
| title_fullStr | Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China |
| title_full_unstemmed | Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China |
| title_short | Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China |
| title_sort | stroke risk among patients with type 2 diabetes mellitus in zhejiang a population based prospective study in china |
| url | http://dx.doi.org/10.1155/2016/6380620 |
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