Loss of interferon regulatory factor-1 prevents lung fibrosis by upregulation of pon1 expression

Loss of interferon regulatory factor-1 prevents lung fibrosis by upregulation of pon1 expression

Abstract Background Interferon regulatory factor-1 (IRF1) is a transcription factor that plays a significant role in various biological processes, including inflammatory injury, viral infection, cell death, and immune responses, and it has been extensively studied in the context of different lung di...

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Bibliographic Details
Main Authors: Aiyuan Zhou, Xiyan Zhang, Xinyue Hu, Tiao Li, Wenzhong Peng, Hang Yang, Dingding Deng, Chunheng Mo, Rongli Lu, Pinhua Pan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Respiratory Research
Subjects:
Lung fibrosis
IRF1
PON1
Ferroptosis
Online Access:https://doi.org/10.1186/s12931-024-02987-9
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