Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient

Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anapl...

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Main Authors: Zeliha Esin Celik, Murat Celik, Erdem Sen, Hakan Cebeci, Ozlem Ata, Cagdas Yavas
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/1280201
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author Zeliha Esin Celik
Murat Celik
Erdem Sen
Hakan Cebeci
Ozlem Ata
Cagdas Yavas
author_facet Zeliha Esin Celik
Murat Celik
Erdem Sen
Hakan Cebeci
Ozlem Ata
Cagdas Yavas
author_sort Zeliha Esin Celik
collection DOAJ
description Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.
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institution Kabale University
issn 2090-6781
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language English
publishDate 2016-01-01
publisher Wiley
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series Case Reports in Pathology
spelling doaj-art-2cf9b5e9c82f48d8ae2d789b7e04dd412025-02-03T05:59:33ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/12802011280201Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative PatientZeliha Esin Celik0Murat Celik1Erdem Sen2Hakan Cebeci3Ozlem Ata4Cagdas Yavas5Pathology Department, Faculty of Medicine, Selçuk University, Alaaddin Keykubat Campus, Selçuklu, 42000 Konya, TurkeyPathology Department, Faculty of Medicine, Selçuk University, TurkeyClinical Oncology Department, Faculty of Medicine, Selçuk University, TurkeyRadiology Department, Faculty of Medicine, Selçuk University, TurkeyClinical Oncology Department, Faculty of Medicine, Selçuk University, TurkeyRadiation Oncology Department, Faculty of Medicine, Selçuk University, TurkeyKaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.http://dx.doi.org/10.1155/2016/1280201
spellingShingle Zeliha Esin Celik
Murat Celik
Erdem Sen
Hakan Cebeci
Ozlem Ata
Cagdas Yavas
Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
Case Reports in Pathology
title Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
title_full Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
title_fullStr Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
title_full_unstemmed Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
title_short Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient
title_sort incidentally detected kaposi sarcoma of adrenal gland with anaplastic features in an hiv negative patient
url http://dx.doi.org/10.1155/2016/1280201
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AT hakancebeci incidentallydetectedkaposisarcomaofadrenalglandwithanaplasticfeaturesinanhivnegativepatient
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