Vascular endothelium state in different types of antihypertensive treatment
Aim. To study ozone therapy effects on blood biochemistry (NO metabolites, NOn-), pro6oxidant and anti-oxdant systems in arterial hypertension (AH) patients.Material and methods. The study was focused on ozone therapy effects on metabolic activity of vascular endothelium and lipid peroxidation (LP)...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2008-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1056 |
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| author | N. V. Kucherenko O. V. Nastradin E. V. Eliseeva E. S. Potapova V. A. Nevzorova |
| author_facet | N. V. Kucherenko O. V. Nastradin E. V. Eliseeva E. S. Potapova V. A. Nevzorova |
| author_sort | N. V. Kucherenko |
| collection | DOAJ |
| description | Aim. To study ozone therapy effects on blood biochemistry (NO metabolites, NOn-), pro6oxidant and anti-oxdant systems in arterial hypertension (AH) patients.Material and methods. The study was focused on ozone therapy effects on metabolic activity of vascular endothelium and lipid peroxidation (LP) activity in 126 patients with stage I-II AH. The levels of NOn- in serum, malone dialdehyde in plasma and superoxide dismutase in red blood cells were measured.Results. In Stage I-II AH, NOn- concentration was reduced, especially in Stage II AH. After one-month combined treatment, plasma NOn- level was similar to that in controls. As early as after first 7 days, ozone therapy resulted in significant LP activity reduction and increased antioxidant potential (AOP), comparing to standard treatment group.Conclusion. Ozone therapy facilitates normalization of vascular endothelium NO-producing function, decrease in LP activity, and AOP restoration. |
| format | Article |
| id | doaj-art-2cf80ff111c447f5a80499534ea0fa85 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2008-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2cf80ff111c447f5a80499534ea0fa852025-08-20T03:43:27Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-02-01712932769Vascular endothelium state in different types of antihypertensive treatmentN. V. Kucherenko0O. V. Nastradin1E. V. Eliseeva2E. S. Potapova3V. A. Nevzorova4Sanatorium “Zhemchuzhny”. NakhodkaVladivostok State Medical University. VladivostokVladivostok State Medical University. VladivostokVladivostok State Medical University. VladivostokVladivostok State Medical University. VladivostokAim. To study ozone therapy effects on blood biochemistry (NO metabolites, NOn-), pro6oxidant and anti-oxdant systems in arterial hypertension (AH) patients.Material and methods. The study was focused on ozone therapy effects on metabolic activity of vascular endothelium and lipid peroxidation (LP) activity in 126 patients with stage I-II AH. The levels of NOn- in serum, malone dialdehyde in plasma and superoxide dismutase in red blood cells were measured.Results. In Stage I-II AH, NOn- concentration was reduced, especially in Stage II AH. After one-month combined treatment, plasma NOn- level was similar to that in controls. As early as after first 7 days, ozone therapy resulted in significant LP activity reduction and increased antioxidant potential (AOP), comparing to standard treatment group.Conclusion. Ozone therapy facilitates normalization of vascular endothelium NO-producing function, decrease in LP activity, and AOP restoration.https://cardiovascular.elpub.ru/jour/article/view/1056arterial hypertensionozone therapyendothelial function |
| spellingShingle | N. V. Kucherenko O. V. Nastradin E. V. Eliseeva E. S. Potapova V. A. Nevzorova Vascular endothelium state in different types of antihypertensive treatment Кардиоваскулярная терапия и профилактика arterial hypertension ozone therapy endothelial function |
| title | Vascular endothelium state in different types of antihypertensive treatment |
| title_full | Vascular endothelium state in different types of antihypertensive treatment |
| title_fullStr | Vascular endothelium state in different types of antihypertensive treatment |
| title_full_unstemmed | Vascular endothelium state in different types of antihypertensive treatment |
| title_short | Vascular endothelium state in different types of antihypertensive treatment |
| title_sort | vascular endothelium state in different types of antihypertensive treatment |
| topic | arterial hypertension ozone therapy endothelial function |
| url | https://cardiovascular.elpub.ru/jour/article/view/1056 |
| work_keys_str_mv | AT nvkucherenko vascularendotheliumstateindifferenttypesofantihypertensivetreatment AT ovnastradin vascularendotheliumstateindifferenttypesofantihypertensivetreatment AT eveliseeva vascularendotheliumstateindifferenttypesofantihypertensivetreatment AT espotapova vascularendotheliumstateindifferenttypesofantihypertensivetreatment AT vanevzorova vascularendotheliumstateindifferenttypesofantihypertensivetreatment |