A brief review of the neuroimaging modalities in schizophrenia and their scope

Schizophrenia is a serious mental disorder characterized by diverse symptoms, including hallucinations, delusions, and disorders in thinking, behavior and cognition. Its etiology is multifactorial involving genetic, environmental, developmental, and neurobiological factors. Neuroimaging studies have...

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Main Authors: Sagarika Ray, Amit Kumar Pal, Partha Sarathi Kundu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Annals of Medical Science and Research
Subjects:
Online Access:https://journals.lww.com/10.4103/amsr.amsr_52_23
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author Sagarika Ray
Amit Kumar Pal
Partha Sarathi Kundu
author_facet Sagarika Ray
Amit Kumar Pal
Partha Sarathi Kundu
author_sort Sagarika Ray
collection DOAJ
description Schizophrenia is a serious mental disorder characterized by diverse symptoms, including hallucinations, delusions, and disorders in thinking, behavior and cognition. Its etiology is multifactorial involving genetic, environmental, developmental, and neurobiological factors. Neuroimaging studies have significantly contributed to understanding the underlying neural abnormalities associated with this disorder. Reduced brain volume was observed in frontal and temporal lobes in most studies using structural imaging techniques. Hypofrontality was observed in functional studies. Neuroimaging also aids in differentiating structural lesions causing symptoms mimicking schizophrenia. However, challenges persist due to variables such as age, gender, comorbidities, therapy history, substance use, and coexisting psychiatric conditions, which are often insufficiently controlled for, in the literature. This review article comprehensively consolidates the diagnostic and prognostic potential of various neuroimaging techniques in schizophrenia.
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spelling doaj-art-2cf14f3f2e0d40098d768a17796d34a92025-08-20T02:55:05ZengWolters Kluwer Medknow PublicationsAnnals of Medical Science and Research2949-785X2024-01-0131333810.4103/amsr.amsr_52_23A brief review of the neuroimaging modalities in schizophrenia and their scopeSagarika RayAmit Kumar PalPartha Sarathi KunduSchizophrenia is a serious mental disorder characterized by diverse symptoms, including hallucinations, delusions, and disorders in thinking, behavior and cognition. Its etiology is multifactorial involving genetic, environmental, developmental, and neurobiological factors. Neuroimaging studies have significantly contributed to understanding the underlying neural abnormalities associated with this disorder. Reduced brain volume was observed in frontal and temporal lobes in most studies using structural imaging techniques. Hypofrontality was observed in functional studies. Neuroimaging also aids in differentiating structural lesions causing symptoms mimicking schizophrenia. However, challenges persist due to variables such as age, gender, comorbidities, therapy history, substance use, and coexisting psychiatric conditions, which are often insufficiently controlled for, in the literature. This review article comprehensively consolidates the diagnostic and prognostic potential of various neuroimaging techniques in schizophrenia.https://journals.lww.com/10.4103/amsr.amsr_52_23functionalhypofrontalitymagnetic resonance imagingneuroimagingpositron emission tomographyschizophreniastructural
spellingShingle Sagarika Ray
Amit Kumar Pal
Partha Sarathi Kundu
A brief review of the neuroimaging modalities in schizophrenia and their scope
Annals of Medical Science and Research
functional
hypofrontality
magnetic resonance imaging
neuroimaging
positron emission tomography
schizophrenia
structural
title A brief review of the neuroimaging modalities in schizophrenia and their scope
title_full A brief review of the neuroimaging modalities in schizophrenia and their scope
title_fullStr A brief review of the neuroimaging modalities in schizophrenia and their scope
title_full_unstemmed A brief review of the neuroimaging modalities in schizophrenia and their scope
title_short A brief review of the neuroimaging modalities in schizophrenia and their scope
title_sort brief review of the neuroimaging modalities in schizophrenia and their scope
topic functional
hypofrontality
magnetic resonance imaging
neuroimaging
positron emission tomography
schizophrenia
structural
url https://journals.lww.com/10.4103/amsr.amsr_52_23
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