Physics-informed machine learning digital twin for reconstructing prostate cancer tumor growth via PSA tests
Abstract Existing prostate cancer monitoring methods, reliant on prostate-specific antigen (PSA) measurements in blood tests often fail to detect tumor growth. We develop a computational framework to reconstruct tumor growth from the PSA integrating physics-based modeling and machine learning in dig...
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| Main Authors: | Daniel Camacho-Gomez, Carlos Borau, Jose Manuel Garcia-Aznar, Maria Jose Gomez-Benito, Mark Girolami, Maria Angeles Perez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-025-01890-x |
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