A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots
BackgroundOptic atrophy (OA) is primarily caused by damage to the retinal pathway system, including widespread degeneration of retinal ganglion cells and axons, leading to visual impairment and blindness. Despite its clinical significance and diverse etiological factors, there is currently a lack of...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1497446/full |
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| author | Liyuan Wang Liyuan Wang Liyuan Wang Tianyang Yu Tianyang Yu Runze Wang Lijuan Fu Lijuan Fu Feixue Dong Feixue Dong Shuang Zhao Shuang Zhao He Sun He Sun Yang Gao |
| author_facet | Liyuan Wang Liyuan Wang Liyuan Wang Tianyang Yu Tianyang Yu Runze Wang Lijuan Fu Lijuan Fu Feixue Dong Feixue Dong Shuang Zhao Shuang Zhao He Sun He Sun Yang Gao |
| author_sort | Liyuan Wang |
| collection | DOAJ |
| description | BackgroundOptic atrophy (OA) is primarily caused by damage to the retinal pathway system, including widespread degeneration of retinal ganglion cells and axons, leading to visual impairment and blindness. Despite its clinical significance and diverse etiological factors, there is currently a lack of comprehensive bibliometric analyses exploring research trends and hotspots within this field.MethodThis study retrieved relevant literature on OA published between 2003 and 2023 from the Web of Science Core Collection database. We conducted a bibliometric analysis using tools such as CiteSpace, VOSviewer, and SCImago Graphica to examine annual publication trends, co-occurrence patterns, collaborative networks among countries and institutions, and the evolution of research hotspots of OA.ResultsA total of 5,274 publications were included in the bibliometric analysis, comprising 4,561 research articles and 713 review articles. The United States emerged as the leading country in OA research, followed by Germany and China. Over the past two decades, the primary research hotspots focused on “mitochondrial dysfunction,” “hereditary optic neuropathy,” “ocular hypertension” and “diagnostic techniques.” Future research trends are likely to revolve around “molecular mechanisms” and “therapeutic targets.”ConclusionThis bibliometric analysis provides an overview of research developments in OA over the past 20 years, highlighting the emphasis on the pathological basis of OA and advancements in diagnostic and therapeutic approaches. Future studies should continue to explore the molecular basis of mitochondrial dysfunction to identify potential gene therapy targets for treating OA. |
| format | Article |
| id | doaj-art-2ceda31cbebf414595b54042caf3fbf5 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-2ceda31cbebf414595b54042caf3fbf52025-01-06T06:58:56ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.14974461497446A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spotsLiyuan Wang0Liyuan Wang1Liyuan Wang2Tianyang Yu3Tianyang Yu4Runze Wang5Lijuan Fu6Lijuan Fu7Feixue Dong8Feixue Dong9Shuang Zhao10Shuang Zhao11He Sun12He Sun13Yang Gao14School of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaGraduate School, Heilongjiang Academy of Traditional Chinese Medicine, Harbin, ChinaSchool of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Acupuncture, Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Rehabilitation Medicine, Qingdao Eighth People’s Hospital, Harbin, ChinaSchool of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaSchool of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaSchool of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaSchool of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Ophthalmology, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ChinaDepartment of Acupuncture, Qingdao Central Hospital, University of Health and Rehabilitation Sciences (Qingdao Central Hospital), Qingdao, ChinaBackgroundOptic atrophy (OA) is primarily caused by damage to the retinal pathway system, including widespread degeneration of retinal ganglion cells and axons, leading to visual impairment and blindness. Despite its clinical significance and diverse etiological factors, there is currently a lack of comprehensive bibliometric analyses exploring research trends and hotspots within this field.MethodThis study retrieved relevant literature on OA published between 2003 and 2023 from the Web of Science Core Collection database. We conducted a bibliometric analysis using tools such as CiteSpace, VOSviewer, and SCImago Graphica to examine annual publication trends, co-occurrence patterns, collaborative networks among countries and institutions, and the evolution of research hotspots of OA.ResultsA total of 5,274 publications were included in the bibliometric analysis, comprising 4,561 research articles and 713 review articles. The United States emerged as the leading country in OA research, followed by Germany and China. Over the past two decades, the primary research hotspots focused on “mitochondrial dysfunction,” “hereditary optic neuropathy,” “ocular hypertension” and “diagnostic techniques.” Future research trends are likely to revolve around “molecular mechanisms” and “therapeutic targets.”ConclusionThis bibliometric analysis provides an overview of research developments in OA over the past 20 years, highlighting the emphasis on the pathological basis of OA and advancements in diagnostic and therapeutic approaches. Future studies should continue to explore the molecular basis of mitochondrial dysfunction to identify potential gene therapy targets for treating OA.https://www.frontiersin.org/articles/10.3389/fmed.2024.1497446/fulloptic atrophybibliometric analysisresearch trendcollaborative networkWeb of Science |
| spellingShingle | Liyuan Wang Liyuan Wang Liyuan Wang Tianyang Yu Tianyang Yu Runze Wang Lijuan Fu Lijuan Fu Feixue Dong Feixue Dong Shuang Zhao Shuang Zhao He Sun He Sun Yang Gao A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots Frontiers in Medicine optic atrophy bibliometric analysis research trend collaborative network Web of Science |
| title | A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots |
| title_full | A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots |
| title_fullStr | A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots |
| title_full_unstemmed | A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots |
| title_short | A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots |
| title_sort | bibliometric analysis of optic atrophy from 2003 to 2023 research trends and hot spots |
| topic | optic atrophy bibliometric analysis research trend collaborative network Web of Science |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1497446/full |
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