The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis
Aim of Review. To conduct analysis of the publications devoted to the new aspects of the pathogenesis of irritable bowel syndrome (IBS) and up-to-date possibilities of the treatment.Key points. The data received in the recent years provide evidence about the fact that in the development of IBS the g...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2013-03-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1186 |
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| author | Ye. A. Poluektova S. Yu. Kuchumova A. A. Sheptulin V. T. Ivashkin |
| author_facet | Ye. A. Poluektova S. Yu. Kuchumova A. A. Sheptulin V. T. Ivashkin |
| author_sort | Ye. A. Poluektova |
| collection | DOAJ |
| description | Aim of Review. To conduct analysis of the publications devoted to the new aspects of the pathogenesis of irritable bowel syndrome (IBS) and up-to-date possibilities of the treatment.Key points. The data received in the recent years provide evidence about the fact that in the development of IBS the genetic factors, the inflammatory changes of the intestinal mucosa and the violation of the balance of the gut microflora play the important role. The treatment of the patients is based on the IBS clinical subtypes and include the antidiarrheal drugs, laxatives and spasmolytics. The good results were obtained during the administration of the combined drug Meteospasmyl (the combination of alverine citrate and simeticone). The topical corticosteroid drugs, mesalazine and probiotics can take their own place in the therapy scheme in the future.Conclusion. The establishing of the IBS new pathogenic mechanisms gives more possibilities for the treatment. |
| format | Article |
| id | doaj-art-2ce8af965d404d9da4059288a6a47288 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2013-03-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-2ce8af965d404d9da4059288a6a472882025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-03-012315765770The treatment of irritable bowel syndrome from the modern views on the disease pathogenesisYe. A. Poluektova0S. Yu. Kuchumova1A. A. Sheptulin2V. T. Ivashkin3I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityAim of Review. To conduct analysis of the publications devoted to the new aspects of the pathogenesis of irritable bowel syndrome (IBS) and up-to-date possibilities of the treatment.Key points. The data received in the recent years provide evidence about the fact that in the development of IBS the genetic factors, the inflammatory changes of the intestinal mucosa and the violation of the balance of the gut microflora play the important role. The treatment of the patients is based on the IBS clinical subtypes and include the antidiarrheal drugs, laxatives and spasmolytics. The good results were obtained during the administration of the combined drug Meteospasmyl (the combination of alverine citrate and simeticone). The topical corticosteroid drugs, mesalazine and probiotics can take their own place in the therapy scheme in the future.Conclusion. The establishing of the IBS new pathogenic mechanisms gives more possibilities for the treatment.https://www.gastro-j.ru/jour/article/view/1186irritable bowel syndromepathogenesisgut microfloratreatment |
| spellingShingle | Ye. A. Poluektova S. Yu. Kuchumova A. A. Sheptulin V. T. Ivashkin The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis Российский журнал гастроэнтерологии, гепатологии, колопроктологии irritable bowel syndrome pathogenesis gut microflora treatment |
| title | The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| title_full | The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| title_fullStr | The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| title_full_unstemmed | The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| title_short | The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| title_sort | treatment of irritable bowel syndrome from the modern views on the disease pathogenesis |
| topic | irritable bowel syndrome pathogenesis gut microflora treatment |
| url | https://www.gastro-j.ru/jour/article/view/1186 |
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