Case report: Pseudoprogression mimicking neoplastic recurrence three months after completion of proton beam therapy for an IDH-mutant astrocytoma CNS WHO grade 3

Case report: Pseudoprogression mimicking neoplastic recurrence three months after completion of proton beam therapy for an IDH-mutant astrocytoma CNS WHO grade 3

BackgroundRadiation-induced changes following proton beam therapy in isocitrate dehydrogenase (IDH)-mutated diffuse central nervous system (CNS) World Health Organization (WHO) grade 2 and 3 gliomas are not well characterized. We present a patient with an IDH-mutant astrocytoma CNS WHO grade 3 treat...

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Bibliographic Details
Main Authors: Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Hanne Blakstad, Cathrine Saxhaug, Pål André Rønning, Pitt Frederik Niehusmann, Katja Werlenius, Malin Blomstrand, Petter Brandal
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
IDH-mutant astrocytoma
diffuse glioma
pseudoprogression
proton beam therapy
radiotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1397912/full
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