Recent advances in 3D printing applications for CNS tumours
Abstract Three-dimensional printing (3DP) has emerged as a transformative technology in the field of central nervous system (CNS) tumours, offering innovative advancements in various aspects of diagnosis, treatment and education. By precisely replicating the microenvironment of CNS tumours, modellin...
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| Language: | English |
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BMC
2025-04-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-025-02483-w |
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| author | Wireko Andrew Awuah Simran Karkhanis Adam Ben-Jaafar Jonathan Sing Huk Kong Krishitha Meenu Mannan Princess Afia Nkrumah-Boateng Joecelyn Kirani Tan Adeleke Oluwaseun Dorcas Vallabh Shet Muhammad Hamza Shah Toufik Abdul-Rahman Oday Atallah |
| author_facet | Wireko Andrew Awuah Simran Karkhanis Adam Ben-Jaafar Jonathan Sing Huk Kong Krishitha Meenu Mannan Princess Afia Nkrumah-Boateng Joecelyn Kirani Tan Adeleke Oluwaseun Dorcas Vallabh Shet Muhammad Hamza Shah Toufik Abdul-Rahman Oday Atallah |
| author_sort | Wireko Andrew Awuah |
| collection | DOAJ |
| description | Abstract Three-dimensional printing (3DP) has emerged as a transformative technology in the field of central nervous system (CNS) tumours, offering innovative advancements in various aspects of diagnosis, treatment and education. By precisely replicating the microenvironment of CNS tumours, modelling tumour vascularisation, and capturing genetic heterogeneity, 3DP enables the development of targeted therapies and personalised treatment strategies. The technology has markedly enhanced preoperative planning and intraoperative guidance, providing highly accurate, patient-specific models that improve tumour localisation, facilitate tailored surgical planning, and offer superior visualisation of complex anatomical structures. Furthermore, 3DP has revolutionised education and training for neurosurgeons, trainees, and patients by delivering realistic simulations that enhance surgical skills and decision-making. Despite its transformative potential, the widespread adoption of 3DP faces challenges, including material biocompatibility issues, high costs, and technical limitations. Furthermore, the ethical and regulatory landscape for 3DP in clinical practice requires further development. This review concludes that while 3DP offers significant promise for advancing CNS tumour treatment, ongoing research is essential to address these challenges and optimising its clinical impact. |
| format | Article |
| id | doaj-art-2ce24297ea7c42699e32064cf75bba59 |
| institution | OA Journals |
| issn | 2047-783X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-2ce24297ea7c42699e32064cf75bba592025-08-20T02:11:46ZengBMCEuropean Journal of Medical Research2047-783X2025-04-0130111910.1186/s40001-025-02483-wRecent advances in 3D printing applications for CNS tumoursWireko Andrew Awuah0Simran Karkhanis1Adam Ben-Jaafar2Jonathan Sing Huk Kong3Krishitha Meenu Mannan4Princess Afia Nkrumah-Boateng5Joecelyn Kirani Tan6Adeleke Oluwaseun Dorcas7Vallabh Shet8Muhammad Hamza Shah9Toufik Abdul-Rahman10Oday Atallah11Department of Research, Toufik’S World Medical AssociationSchool of Medicine and Dentistry, University of Central LancashireSchool of Medicine, University College DublinSchool of Medicine, College of Medical & Veterinary Life Sciences, University of GlasgowSchool of Medicine, Dentistry & Biomedical Sciences, Queen’S University BelfastUniversity of Ghana Medical SchoolFaculty of Biology, Medicine and Health, University of ManchesterDepartment of Research, Toufik’S World Medical AssociationDepartment of Internal Medicine, University of Connecticut New Britain ProgramSchool of Medicine, Dentistry & Biomedical Sciences, Queen’S University BelfastDepartment of Research, Toufik’S World Medical AssociationDepartment of Neurosurgery, Carl Von Ossietzky University OldenburgAbstract Three-dimensional printing (3DP) has emerged as a transformative technology in the field of central nervous system (CNS) tumours, offering innovative advancements in various aspects of diagnosis, treatment and education. By precisely replicating the microenvironment of CNS tumours, modelling tumour vascularisation, and capturing genetic heterogeneity, 3DP enables the development of targeted therapies and personalised treatment strategies. The technology has markedly enhanced preoperative planning and intraoperative guidance, providing highly accurate, patient-specific models that improve tumour localisation, facilitate tailored surgical planning, and offer superior visualisation of complex anatomical structures. Furthermore, 3DP has revolutionised education and training for neurosurgeons, trainees, and patients by delivering realistic simulations that enhance surgical skills and decision-making. Despite its transformative potential, the widespread adoption of 3DP faces challenges, including material biocompatibility issues, high costs, and technical limitations. Furthermore, the ethical and regulatory landscape for 3DP in clinical practice requires further development. This review concludes that while 3DP offers significant promise for advancing CNS tumour treatment, ongoing research is essential to address these challenges and optimising its clinical impact.https://doi.org/10.1186/s40001-025-02483-wThree dimensional printingCNS tumoursNeuro oncologyNeurosurgery |
| spellingShingle | Wireko Andrew Awuah Simran Karkhanis Adam Ben-Jaafar Jonathan Sing Huk Kong Krishitha Meenu Mannan Princess Afia Nkrumah-Boateng Joecelyn Kirani Tan Adeleke Oluwaseun Dorcas Vallabh Shet Muhammad Hamza Shah Toufik Abdul-Rahman Oday Atallah Recent advances in 3D printing applications for CNS tumours European Journal of Medical Research Three dimensional printing CNS tumours Neuro oncology Neurosurgery |
| title | Recent advances in 3D printing applications for CNS tumours |
| title_full | Recent advances in 3D printing applications for CNS tumours |
| title_fullStr | Recent advances in 3D printing applications for CNS tumours |
| title_full_unstemmed | Recent advances in 3D printing applications for CNS tumours |
| title_short | Recent advances in 3D printing applications for CNS tumours |
| title_sort | recent advances in 3d printing applications for cns tumours |
| topic | Three dimensional printing CNS tumours Neuro oncology Neurosurgery |
| url | https://doi.org/10.1186/s40001-025-02483-w |
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