Hedgehog Signalling is Downregulated in Celiac Disease

BACKGROUND: Celiac disease (CD) is a common autoimmune disorder of the small intestine that occurs in genetically predisposed individuals. Animal studies have suggested that the hedgehog (Hh) signalling pathway is involved in gut inflammation, injury and repair.

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Main Authors: Rui Liang, Rupert Hinds, Helen E Abud, Wei Cheng
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2013/676430
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author Rui Liang
Rupert Hinds
Helen E Abud
Wei Cheng
author_facet Rui Liang
Rupert Hinds
Helen E Abud
Wei Cheng
author_sort Rui Liang
collection DOAJ
description BACKGROUND: Celiac disease (CD) is a common autoimmune disorder of the small intestine that occurs in genetically predisposed individuals. Animal studies have suggested that the hedgehog (Hh) signalling pathway is involved in gut inflammation, injury and repair.
format Article
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institution OA Journals
issn 0835-7900
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-2cdd411371f94f57aeaed34e6de8aa322025-08-20T02:38:52ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-01271e5e710.1155/2013/676430Hedgehog Signalling is Downregulated in Celiac DiseaseRui Liang0Rupert Hinds1Helen E Abud2Wei Cheng3Key Laboratory of Developmental Diseases in Childhood (Chongqing Medical University), Ministry of Education, ChinaDepartment of Paediatrics, Southern Health, AustraliaDepartment of Anatomy and Developmental Biology, Monash University, Victoria, AustraliaKey Laboratory of Developmental Diseases in Childhood (Chongqing Medical University), Ministry of Education, ChinaBACKGROUND: Celiac disease (CD) is a common autoimmune disorder of the small intestine that occurs in genetically predisposed individuals. Animal studies have suggested that the hedgehog (Hh) signalling pathway is involved in gut inflammation, injury and repair.http://dx.doi.org/10.1155/2013/676430
spellingShingle Rui Liang
Rupert Hinds
Helen E Abud
Wei Cheng
Hedgehog Signalling is Downregulated in Celiac Disease
Canadian Journal of Gastroenterology
title Hedgehog Signalling is Downregulated in Celiac Disease
title_full Hedgehog Signalling is Downregulated in Celiac Disease
title_fullStr Hedgehog Signalling is Downregulated in Celiac Disease
title_full_unstemmed Hedgehog Signalling is Downregulated in Celiac Disease
title_short Hedgehog Signalling is Downregulated in Celiac Disease
title_sort hedgehog signalling is downregulated in celiac disease
url http://dx.doi.org/10.1155/2013/676430
work_keys_str_mv AT ruiliang hedgehogsignallingisdownregulatedinceliacdisease
AT ruperthinds hedgehogsignallingisdownregulatedinceliacdisease
AT heleneabud hedgehogsignallingisdownregulatedinceliacdisease
AT weicheng hedgehogsignallingisdownregulatedinceliacdisease