APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading

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Bibliographic Details
Main Authors: Jing Feng, Xiwen Ma, Jianping Ye
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525001200
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author Jing Feng
Xiwen Ma
Jianping Ye
author_facet Jing Feng
Xiwen Ma
Jianping Ye
author_sort Jing Feng
collection DOAJ
format Article
id doaj-art-2cdd2ff27fa2416fa64c2c3f1d777798
institution Kabale University
issn 2211-3835
language English
publishDate 2025-08-01
publisher Elsevier
record_format Article
series Acta Pharmaceutica Sinica B
spelling doaj-art-2cdd2ff27fa2416fa64c2c3f1d7777982025-08-20T05:06:28ZengElsevierActa Pharmaceutica Sinica B2211-38352025-08-011584306430810.1016/j.apsb.2025.03.001APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloadingJing Feng0Xiwen Ma1Jianping Ye2Institute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, ChinaInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, ChinaInstitute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China; Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450001, China; Corresponding author.http://www.sciencedirect.com/science/article/pii/S2211383525001200APOE2APOE3APOE4LipofuscinLDLRAlzheimer's disease
spellingShingle Jing Feng
Xiwen Ma
Jianping Ye
APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
Acta Pharmaceutica Sinica B
APOE2
APOE3
APOE4
Lipofuscin
LDLR
Alzheimer's disease
title APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
title_full APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
title_fullStr APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
title_full_unstemmed APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
title_short APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
title_sort apoe2 reduces risk of alzheimer s disease by protection of lysosomes from lipid overloading
topic APOE2
APOE3
APOE4
Lipofuscin
LDLR
Alzheimer's disease
url http://www.sciencedirect.com/science/article/pii/S2211383525001200
work_keys_str_mv AT jingfeng apoe2reducesriskofalzheimersdiseasebyprotectionoflysosomesfromlipidoverloading
AT xiwenma apoe2reducesriskofalzheimersdiseasebyprotectionoflysosomesfromlipidoverloading
AT jianpingye apoe2reducesriskofalzheimersdiseasebyprotectionoflysosomesfromlipidoverloading