Antbacterial Property of Ethanolic Extract from the Leaves of Acacia nilotica WILD. ON Staphylococcus aureus AND Pseudomonas aeruginosa
The traditional medicine involves the use of different plants or the bioactive constituents of different plants to cure diseases and this was done long time ago based on the history of human being Acacia nilotica is a multipurpose plant belonging to the family Mimosaceae. Commonly known as Prickly...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Umaru Musa Yar'adua University, Katsina, Nigeria
2018-06-01
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| Series: | UMYU Journal of Microbiology Research |
| Subjects: | |
| Online Access: | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/258 |
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| Summary: | The traditional medicine involves the use of different plants or the bioactive constituents of different plants to cure diseases and this was done long time ago based on the history of human being Acacia nilotica is a multipurpose plant belonging to the family Mimosaceae. Commonly known as Prickly acacia in English and Bagaruwa in Hausa language, It have been used traditionally to treat infections. The present study aimed at investigating antibacterial activity of Acacia nilotica Wild. ethanolic leaves extract and its column fractions against selected multi drug resistant Staphylococcus aureus and Pseudomonas aeruginosa. Extract of Acacia nilotica were prepared using ethanol on the basis of their increasing polarity with varying concentrations and were screened for the antibacterial activity using disc diffusion assay. The crude extract was further subjected to column and thin layer chromatography (TLC) for bioassay guided fractionation; thus a total of 74 fractions were obtained. The fractions were screened for the antibacterial activity, fraction 6 (CF6) showed highest zone of inhibition of 12 mm and 9 mm against S. aureus and P. aeruginosa respectively. Therefore this study demonstrated the value of A. nilotica plant as alternative for the treatment of bacterial infections. The most active fraction can be further explored to isolate and characterize the bioactive components responsible for biological activity to develop new antibacterial drug.
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| ISSN: | 2616-0668 2814-1822 |