Ixodic Tick-Borne Borreliosis in the Krasnodar Krai
Aim. Clinical, epidemic and laboratory characterisation of ixodic tick-borne borreliosis in order to improve the early diagnosis of the disease and the timely etiotropic therapy.Materials and methods. The medical histories of 257 patients with ixodic tick-borne borreliosis treated in the regional in...
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| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2019-12-01
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| Series: | Кубанский научный медицинский вестник |
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| Online Access: | https://ksma.elpub.ru/jour/article/view/2012 |
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| author | Darya Yu. Moshkova Marina G. Avdeeva Ludmila P. Blazhnyaya |
| author_facet | Darya Yu. Moshkova Marina G. Avdeeva Ludmila P. Blazhnyaya |
| author_sort | Darya Yu. Moshkova |
| collection | DOAJ |
| description | Aim. Clinical, epidemic and laboratory characterisation of ixodic tick-borne borreliosis in order to improve the early diagnosis of the disease and the timely etiotropic therapy.Materials and methods. The medical histories of 257 patients with ixodic tick-borne borreliosis treated in the regional infectious diseases hospital in Krasnodar from 2004 to 2018 were analysed. The data of the epidemiological history, the clinical manifestations of the disease, the results of laboratory and instrumental studies, as well as the principles of therapy were analysed. Results. The incidence of ixodic tick-borne borreliosis in the Krasnodar Krai is characterised by spring-summer seasonality, the predominance among women over 45, and urban residents. The disease has an acute course (85.9%), occurs mainly in the erythema form with little pronounced symptoms of intoxication, a typical ring-shaped erythema, which large dimensions remain longer in women. During the non-erythemic form of the disease, the development of serous meningitis and encephalomeningitis with impaired cerebral blood fl ow as well as the changes in corticocortical relationships were observed. During the sub-acute course, radiculopathy and polyneuropathy, as well as diffuse changes of the myocardium with conduction disturbance and the development of atrioventricular block, arthralgia and arthritis/arthrosis were registered. The increase in LDH, CPK and transaminase was observed for all forms of the disease.Conclusion. In connection with the formation of a natural ixodic tick-borne borreliosis focus on the territory of the Krasnodar Krai, it is necessary to exclude this disease in patients with the signs of fever, weakness, and erythema at the site of tick suction. The tendency of ixodic tickborne borreliosis to the long course with the development of multiorgan pathology causes the need for follow-up observation of recovered patients both by an infectious disease specialist and narrow specialists (a neurologist, rheumatologist or cardiologist). |
| format | Article |
| id | doaj-art-2cd48d5aee4246f7b1105ef45189eb02 |
| institution | Kabale University |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| publishDate | 2019-12-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj-art-2cd48d5aee4246f7b1105ef45189eb022025-08-20T03:57:13ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442019-12-01266496010.25207/1608-6228-2019-26-6-49-601150Ixodic Tick-Borne Borreliosis in the Krasnodar KraiDarya Yu. Moshkova0Marina G. Avdeeva1Ludmila P. Blazhnyaya2Kuban State Medical UniversityKuban State Medical UniversityKuban State Medical UniversityAim. Clinical, epidemic and laboratory characterisation of ixodic tick-borne borreliosis in order to improve the early diagnosis of the disease and the timely etiotropic therapy.Materials and methods. The medical histories of 257 patients with ixodic tick-borne borreliosis treated in the regional infectious diseases hospital in Krasnodar from 2004 to 2018 were analysed. The data of the epidemiological history, the clinical manifestations of the disease, the results of laboratory and instrumental studies, as well as the principles of therapy were analysed. Results. The incidence of ixodic tick-borne borreliosis in the Krasnodar Krai is characterised by spring-summer seasonality, the predominance among women over 45, and urban residents. The disease has an acute course (85.9%), occurs mainly in the erythema form with little pronounced symptoms of intoxication, a typical ring-shaped erythema, which large dimensions remain longer in women. During the non-erythemic form of the disease, the development of serous meningitis and encephalomeningitis with impaired cerebral blood fl ow as well as the changes in corticocortical relationships were observed. During the sub-acute course, radiculopathy and polyneuropathy, as well as diffuse changes of the myocardium with conduction disturbance and the development of atrioventricular block, arthralgia and arthritis/arthrosis were registered. The increase in LDH, CPK and transaminase was observed for all forms of the disease.Conclusion. In connection with the formation of a natural ixodic tick-borne borreliosis focus on the territory of the Krasnodar Krai, it is necessary to exclude this disease in patients with the signs of fever, weakness, and erythema at the site of tick suction. The tendency of ixodic tickborne borreliosis to the long course with the development of multiorgan pathology causes the need for follow-up observation of recovered patients both by an infectious disease specialist and narrow specialists (a neurologist, rheumatologist or cardiologist).https://ksma.elpub.ru/jour/article/view/2012borreliosisepidemiologyclinicdiagnosistreatment |
| spellingShingle | Darya Yu. Moshkova Marina G. Avdeeva Ludmila P. Blazhnyaya Ixodic Tick-Borne Borreliosis in the Krasnodar Krai Кубанский научный медицинский вестник borreliosis epidemiology clinic diagnosis treatment |
| title | Ixodic Tick-Borne Borreliosis in the Krasnodar Krai |
| title_full | Ixodic Tick-Borne Borreliosis in the Krasnodar Krai |
| title_fullStr | Ixodic Tick-Borne Borreliosis in the Krasnodar Krai |
| title_full_unstemmed | Ixodic Tick-Borne Borreliosis in the Krasnodar Krai |
| title_short | Ixodic Tick-Borne Borreliosis in the Krasnodar Krai |
| title_sort | ixodic tick borne borreliosis in the krasnodar krai |
| topic | borreliosis epidemiology clinic diagnosis treatment |
| url | https://ksma.elpub.ru/jour/article/view/2012 |
| work_keys_str_mv | AT daryayumoshkova ixodictickborneborreliosisinthekrasnodarkrai AT marinagavdeeva ixodictickborneborreliosisinthekrasnodarkrai AT ludmilapblazhnyaya ixodictickborneborreliosisinthekrasnodarkrai |