Primary percutaneous stenting above the ampulla versus endoscopic drainage for unresectable malignant hilar biliary obstruction (TESLA RCT): study protocol for a multicenter randomized controlled trial

Primary percutaneous stenting above the ampulla versus endoscopic drainage for unresectable malignant hilar biliary obstruction (TESLA RCT): study protocol for a multicenter randomized controlled trial

Abstract Background Patients with malignant hilar biliary obstruction typically present with painless jaundice. They commonly have perihilar cholangiocarcinoma (pCCA), but also intrahepatic cholangiocarcinoma, gallbladder cancer, and metastases to the liver hilum can present with hilar biliary obstr...

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Main Authors: M. Rousian, V. van Verschuer, S. Franssen, D. Bijdevaate, R. P.H. Bokkers, A. E. Braat, J. de Bruijne, M. J. Bruno, M. C. Burgmans, O. M. van Delden, M. Dewulf, J. I. Erdmann, J. Hagendoorn, B. van der Holt, F. J.H. Hoogwater, A. Inderson, C. van der Leij, B. Mohseny, J. W. Poley, M. L.J. Smits, F. G.I. van Vilsteren, R. P. Voermans, I. A.J. Zijlstra, L. M.J.W. van Driel, B. Groot Koerkamp
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Malignant hilar biliary obstruction
Primary percutaneous stenting
Endoscopic biliary drainage
Randomized controlled trial
Major complications
Overall survival
Online Access:https://doi.org/10.1186/s12885-025-14158-0
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