Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults
Purpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The present study investigated the predictive factors for disease severity in young adults.Method: Our study is a descriptive cross-sectional study. A total of 399 patients with...
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Sakarya University
2024-03-01
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| Series: | Sakarya Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2106295 |
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| author | Elif Köse Gökcen Gürkök Budak Hüseyin Doğuş Okan Aylin Çalıca Utku Aziz Öğütlü Ertuğrul Güçlü Oğuz Karabay Aslı Vatan |
| author_facet | Elif Köse Gökcen Gürkök Budak Hüseyin Doğuş Okan Aylin Çalıca Utku Aziz Öğütlü Ertuğrul Güçlü Oğuz Karabay Aslı Vatan |
| author_sort | Elif Köse |
| collection | DOAJ |
| description | Purpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The present study investigated the predictive factors for disease severity in young adults.Method: Our study is a descriptive cross-sectional study. A total of 399 patients with SARS-CoV-2 aged under 60 who had been hospitalized at our hospital were retrospectively evaluated. Patients were stratified into mild, moderate, severe, and critical groups according to their respiratory rate, SpO2, and PaO2/FiO2 levels. The relationship between the signs and symptoms on hospital admission and the disease severity was evaluated.Results: The patients were classified as mild (n:112), moderate (n:192), severe and critical (n:95) according to disease severity. The mean age was 44. 43 of 399 patients were followed in the intensive care unit, and 17 patients died. According to the binary logistic regression analysis, advanced age, hypertension, dyspnea on admission, elevated CRP, decreased lymphocyte and eosinophil count, multiple bilateral ground glass appearances, and consolidation independently predicted the severity of the disease.Conclusion: The signs and symptoms should be evaluated in detail also in young patients with SARS-CoV-2. If risk factors are detected, they should be monitored more closely to predict a poor prognosis.. |
| format | Article |
| id | doaj-art-2ccf33fb57164edf9425e256de84e9ae |
| institution | DOAJ |
| issn | 2146-409X |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Sakarya University |
| record_format | Article |
| series | Sakarya Tıp Dergisi |
| spelling | doaj-art-2ccf33fb57164edf9425e256de84e9ae2025-08-20T03:10:42ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2024-03-01141111910.31832/smj.103020828Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young AdultsElif Köse0https://orcid.org/0000-0002-2232-4538Gökcen Gürkök Budak1https://orcid.org/0000-0002-6317-7685Hüseyin Doğuş Okan2https://orcid.org/0000-0001-6729-8938Aylin Çalıca Utku3https://orcid.org/0000-0002-9302-5842Aziz Öğütlü4https://orcid.org/0000-0003-3840-4038Ertuğrul Güçlü5https://orcid.org/0000-0003-2860-2831Oğuz Karabay6https://orcid.org/0000-0003-1514-1685Aslı Vatan7https://orcid.org/0000-0003-4157-9226SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİSAKARYA ÜNİVERSİTESİPurpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The present study investigated the predictive factors for disease severity in young adults.Method: Our study is a descriptive cross-sectional study. A total of 399 patients with SARS-CoV-2 aged under 60 who had been hospitalized at our hospital were retrospectively evaluated. Patients were stratified into mild, moderate, severe, and critical groups according to their respiratory rate, SpO2, and PaO2/FiO2 levels. The relationship between the signs and symptoms on hospital admission and the disease severity was evaluated.Results: The patients were classified as mild (n:112), moderate (n:192), severe and critical (n:95) according to disease severity. The mean age was 44. 43 of 399 patients were followed in the intensive care unit, and 17 patients died. According to the binary logistic regression analysis, advanced age, hypertension, dyspnea on admission, elevated CRP, decreased lymphocyte and eosinophil count, multiple bilateral ground glass appearances, and consolidation independently predicted the severity of the disease.Conclusion: The signs and symptoms should be evaluated in detail also in young patients with SARS-CoV-2. If risk factors are detected, they should be monitored more closely to predict a poor prognosis..https://dergipark.org.tr/tr/download/article-file/2106295sars-cov-2young adultprognostic factorssars-cov-2genç yetişkinprognostik faktörler |
| spellingShingle | Elif Köse Gökcen Gürkök Budak Hüseyin Doğuş Okan Aylin Çalıca Utku Aziz Öğütlü Ertuğrul Güçlü Oğuz Karabay Aslı Vatan Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults Sakarya Tıp Dergisi sars-cov-2 young adult prognostic factors sars-cov-2 genç yetişkin prognostik faktörler |
| title | Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults |
| title_full | Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults |
| title_fullStr | Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults |
| title_full_unstemmed | Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults |
| title_short | Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults |
| title_sort | predictive factors for severe and critical coronavirus disease 19 in young adults |
| topic | sars-cov-2 young adult prognostic factors sars-cov-2 genç yetişkin prognostik faktörler |
| url | https://dergipark.org.tr/tr/download/article-file/2106295 |
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