Amyloid‐based functional materials and their application in flexible sensors

Abstract Flexible electronic devices have garnered increasing attention for their applications in wearable devices, biomedical systems, soft robots, and flexible displays. However, the current sensors face limitations regarding low sensitivity, poor stability, and inadequate adhesion bonding between...

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Main Authors: Yage Wu, Jiqing Zhang, Ling Li, Jian Zhao, Peng Yang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Electron
Subjects:
Online Access:https://doi.org/10.1002/elt2.59
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author Yage Wu
Jiqing Zhang
Ling Li
Jian Zhao
Peng Yang
author_facet Yage Wu
Jiqing Zhang
Ling Li
Jian Zhao
Peng Yang
author_sort Yage Wu
collection DOAJ
description Abstract Flexible electronic devices have garnered increasing attention for their applications in wearable devices, biomedical systems, soft robots, and flexible displays. However, the current sensors face limitations regarding low sensitivity, poor stability, and inadequate adhesion bonding between stimuli‐responsive functional materials and flexible substrates. To overcome these challenges and enable the further development of sensor devices, surface modification of stimuli‐responsive materials with amyloid aggregates has emerged as a promising approach to enhance functionality and create superior multifunctional sensors. This review presents recent research advancements in the flexible sensors based on protein amyloid aggregation. The article begins by explaining the basic principles of protein amyloid aggregation, followed by outlining the process of preparing 1D to 3D amyloid‐based composite materials. Finally, it discusses the utilization of protein amyloid aggregation as a surface modification technique for developing flexible sensors. Based on this foundation, we identify the shortcomings associated with protein amyloid aggregate composites and propose possible solutions to address them. We believe that comprehensive investigations in this area will expedite the development of high‐performance flexible sensors with high sensitivity, high structural stability, and strong interface adhesion, especially the implantable flexible sensors for health monitoring.
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publishDate 2025-02-01
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spelling doaj-art-2ccab34f371c43eeafc950d76d372b3c2025-08-20T02:36:28ZengWileyElectron2751-26062751-26142025-02-0131n/an/a10.1002/elt2.59Amyloid‐based functional materials and their application in flexible sensorsYage Wu0Jiqing Zhang1Ling Li2Jian Zhao3Peng Yang4Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an ChinaKey Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an ChinaKey Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an ChinaKey Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an ChinaKey Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an ChinaAbstract Flexible electronic devices have garnered increasing attention for their applications in wearable devices, biomedical systems, soft robots, and flexible displays. However, the current sensors face limitations regarding low sensitivity, poor stability, and inadequate adhesion bonding between stimuli‐responsive functional materials and flexible substrates. To overcome these challenges and enable the further development of sensor devices, surface modification of stimuli‐responsive materials with amyloid aggregates has emerged as a promising approach to enhance functionality and create superior multifunctional sensors. This review presents recent research advancements in the flexible sensors based on protein amyloid aggregation. The article begins by explaining the basic principles of protein amyloid aggregation, followed by outlining the process of preparing 1D to 3D amyloid‐based composite materials. Finally, it discusses the utilization of protein amyloid aggregation as a surface modification technique for developing flexible sensors. Based on this foundation, we identify the shortcomings associated with protein amyloid aggregate composites and propose possible solutions to address them. We believe that comprehensive investigations in this area will expedite the development of high‐performance flexible sensors with high sensitivity, high structural stability, and strong interface adhesion, especially the implantable flexible sensors for health monitoring.https://doi.org/10.1002/elt2.59amyloidcomposite coatingflexible sensorsprotein aggregationsurface modification
spellingShingle Yage Wu
Jiqing Zhang
Ling Li
Jian Zhao
Peng Yang
Amyloid‐based functional materials and their application in flexible sensors
Electron
amyloid
composite coating
flexible sensors
protein aggregation
surface modification
title Amyloid‐based functional materials and their application in flexible sensors
title_full Amyloid‐based functional materials and their application in flexible sensors
title_fullStr Amyloid‐based functional materials and their application in flexible sensors
title_full_unstemmed Amyloid‐based functional materials and their application in flexible sensors
title_short Amyloid‐based functional materials and their application in flexible sensors
title_sort amyloid based functional materials and their application in flexible sensors
topic amyloid
composite coating
flexible sensors
protein aggregation
surface modification
url https://doi.org/10.1002/elt2.59
work_keys_str_mv AT yagewu amyloidbasedfunctionalmaterialsandtheirapplicationinflexiblesensors
AT jiqingzhang amyloidbasedfunctionalmaterialsandtheirapplicationinflexiblesensors
AT lingli amyloidbasedfunctionalmaterialsandtheirapplicationinflexiblesensors
AT jianzhao amyloidbasedfunctionalmaterialsandtheirapplicationinflexiblesensors
AT pengyang amyloidbasedfunctionalmaterialsandtheirapplicationinflexiblesensors