Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity
The aim of this study was to analyze the effects of a 4-week-long consumption of glucomannan-enriched, aronia juice-based supplement on anthropometric parameters, membrane fatty acid profile, and status of antioxidant enzymes in erythrocytes obtained from postmenopausal women with abdominal obesity....
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/869250 |
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| author | Nevena Kardum Gordana Petrović-Oggiano Marija Takic Natalija Glibetić Manja Zec Jasmina Debeljak-Martacic Aleksandra Konić-Ristić |
| author_facet | Nevena Kardum Gordana Petrović-Oggiano Marija Takic Natalija Glibetić Manja Zec Jasmina Debeljak-Martacic Aleksandra Konić-Ristić |
| author_sort | Nevena Kardum |
| collection | DOAJ |
| description | The aim of this study was to analyze the effects of a 4-week-long consumption of glucomannan-enriched, aronia juice-based supplement on anthropometric parameters, membrane fatty acid profile, and status of antioxidant enzymes in erythrocytes obtained from postmenopausal women with abdominal obesity. Twenty women aged 45–65 with a mean body mass index (BMI) of 36.1 ± 4.4 kg/m2 and waist circumference of 104.8 ± 10.1 cm were enrolled. Participants were instructed to consume 100 mL of supplement per day as part of their regular diet. A significant increase in the content of n-3 (P<0.05) polyunsaturated fatty acids in membrane phospholipids was observed, with a marked increase in the level of docosahexaenoic fatty acid (P<0.05). Accordingly, a decrease in the n-6 and n-3 fatty acids ratio was observed (P<0.05). The observed effects were accompanied with an increase in glutathione peroxidase activity (P<0.05). Values for BMI (P<0.001), waist circumference (P<0.001), and systolic blood pressure (P<0.05) were significantly lower after the intervention. The obtained results indicate a positive impact of tested supplement on cellular oxidative damage, blood pressure, and anthropometric indices of obesity. |
| format | Article |
| id | doaj-art-2cc9178eb92d4e86925b99b55ab94c44 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-2cc9178eb92d4e86925b99b55ab94c442025-08-20T03:55:12ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/869250869250Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal ObesityNevena Kardum0Gordana Petrović-Oggiano1Marija Takic2Natalija Glibetić3Manja Zec4Jasmina Debeljak-Martacic5Aleksandra Konić-Ristić6Centre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Drive Subotića 4, 11000 Belgrade, SerbiaThe aim of this study was to analyze the effects of a 4-week-long consumption of glucomannan-enriched, aronia juice-based supplement on anthropometric parameters, membrane fatty acid profile, and status of antioxidant enzymes in erythrocytes obtained from postmenopausal women with abdominal obesity. Twenty women aged 45–65 with a mean body mass index (BMI) of 36.1 ± 4.4 kg/m2 and waist circumference of 104.8 ± 10.1 cm were enrolled. Participants were instructed to consume 100 mL of supplement per day as part of their regular diet. A significant increase in the content of n-3 (P<0.05) polyunsaturated fatty acids in membrane phospholipids was observed, with a marked increase in the level of docosahexaenoic fatty acid (P<0.05). Accordingly, a decrease in the n-6 and n-3 fatty acids ratio was observed (P<0.05). The observed effects were accompanied with an increase in glutathione peroxidase activity (P<0.05). Values for BMI (P<0.001), waist circumference (P<0.001), and systolic blood pressure (P<0.05) were significantly lower after the intervention. The obtained results indicate a positive impact of tested supplement on cellular oxidative damage, blood pressure, and anthropometric indices of obesity.http://dx.doi.org/10.1155/2014/869250 |
| spellingShingle | Nevena Kardum Gordana Petrović-Oggiano Marija Takic Natalija Glibetić Manja Zec Jasmina Debeljak-Martacic Aleksandra Konić-Ristić Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity The Scientific World Journal |
| title | Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity |
| title_full | Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity |
| title_fullStr | Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity |
| title_full_unstemmed | Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity |
| title_short | Effects of Glucomannan-Enriched, Aronia Juice-Based Supplement on Cellular Antioxidant Enzymes and Membrane Lipid Status in Subjects with Abdominal Obesity |
| title_sort | effects of glucomannan enriched aronia juice based supplement on cellular antioxidant enzymes and membrane lipid status in subjects with abdominal obesity |
| url | http://dx.doi.org/10.1155/2014/869250 |
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