Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.

Attract-and-kill strategies are effective, sustainable pest control methods. Formulations combining the insecticide spinosad, at a lower dose than conventional methods, with the Drosophila-associated yeast Hanseniaspora uvarum have shown promising results. Recently, Saccharomycopsis vini was identif...

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Main Authors: Claire Duménil, Urban Spitaler, Guillermo Rehermann, Flavia Bianchi, Riccardo Favaro, Irene Castellan, Silvia Schmidt, Daniela Eisenstecken, Paul G Becher, Sergio Angeli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323653
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author Claire Duménil
Urban Spitaler
Guillermo Rehermann
Flavia Bianchi
Riccardo Favaro
Irene Castellan
Silvia Schmidt
Daniela Eisenstecken
Paul G Becher
Sergio Angeli
author_facet Claire Duménil
Urban Spitaler
Guillermo Rehermann
Flavia Bianchi
Riccardo Favaro
Irene Castellan
Silvia Schmidt
Daniela Eisenstecken
Paul G Becher
Sergio Angeli
author_sort Claire Duménil
collection DOAJ
description Attract-and-kill strategies are effective, sustainable pest control methods. Formulations combining the insecticide spinosad, at a lower dose than conventional methods, with the Drosophila-associated yeast Hanseniaspora uvarum have shown promising results. Recently, Saccharomycopsis vini was identified as the most attractive yeast for ovipositing females. In this study, the potential of S. vini for use in attract-and-kill formulations against D. suzukii was evaluated alongside H. uvarum. Behavioural assays demonstrated that D. suzukii preferred S. vini when both yeasts are simultaneously present in a close range setting but was attracted to both in long range attraction assays. In efficacy assays, S. vini and H. uvarum were equally efficient at reducing oviposition and increasing mortality in formulation with spinosad. Offering yeast formulations at the foraging sites of trained honey bees did not stimulate more feeding when compared to sugar syrup. The characterisation of the organic volatile compounds released from the cultures demonstrated that S. vini and H. uvarum were composed of overlapping as well as distinct chemicals. The antennally active compounds ethyl acetate and ethyl propanoate were abundant in the more attractive S. vini and H. uvarum, while the compounds 3-methyl-1-butanol and 2-methylthiolan-3-one were more abundant in the less attractive S. cerevisiae. These chemicals may be further studied as possible attractants or repellents for D. suzukii. We propose S. vini as a new yeast with potential for use in integrated pest management, with a distinctive volatile profile while maintaining a similar efficacy compared to H. uvarum against D. suzukii. Neither H. uvarum nor S. vini stimulated honey bee foraging behaviour, suggesting that both yeast-based attract-and-kill formulations pose a low non-target risk to honey bees.
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spelling doaj-art-2cc5a03e58eb4ee4a05b863e3108e9562025-08-20T01:52:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01205e032365310.1371/journal.pone.0323653Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.Claire DuménilUrban SpitalerGuillermo RehermannFlavia BianchiRiccardo FavaroIrene CastellanSilvia SchmidtDaniela EisensteckenPaul G BecherSergio AngeliAttract-and-kill strategies are effective, sustainable pest control methods. Formulations combining the insecticide spinosad, at a lower dose than conventional methods, with the Drosophila-associated yeast Hanseniaspora uvarum have shown promising results. Recently, Saccharomycopsis vini was identified as the most attractive yeast for ovipositing females. In this study, the potential of S. vini for use in attract-and-kill formulations against D. suzukii was evaluated alongside H. uvarum. Behavioural assays demonstrated that D. suzukii preferred S. vini when both yeasts are simultaneously present in a close range setting but was attracted to both in long range attraction assays. In efficacy assays, S. vini and H. uvarum were equally efficient at reducing oviposition and increasing mortality in formulation with spinosad. Offering yeast formulations at the foraging sites of trained honey bees did not stimulate more feeding when compared to sugar syrup. The characterisation of the organic volatile compounds released from the cultures demonstrated that S. vini and H. uvarum were composed of overlapping as well as distinct chemicals. The antennally active compounds ethyl acetate and ethyl propanoate were abundant in the more attractive S. vini and H. uvarum, while the compounds 3-methyl-1-butanol and 2-methylthiolan-3-one were more abundant in the less attractive S. cerevisiae. These chemicals may be further studied as possible attractants or repellents for D. suzukii. We propose S. vini as a new yeast with potential for use in integrated pest management, with a distinctive volatile profile while maintaining a similar efficacy compared to H. uvarum against D. suzukii. Neither H. uvarum nor S. vini stimulated honey bee foraging behaviour, suggesting that both yeast-based attract-and-kill formulations pose a low non-target risk to honey bees.https://doi.org/10.1371/journal.pone.0323653
spellingShingle Claire Duménil
Urban Spitaler
Guillermo Rehermann
Flavia Bianchi
Riccardo Favaro
Irene Castellan
Silvia Schmidt
Daniela Eisenstecken
Paul G Becher
Sergio Angeli
Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
PLoS ONE
title Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
title_full Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
title_fullStr Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
title_full_unstemmed Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
title_short Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity.
title_sort yeast based attract and kill strategies for drosophila suzukii management without disrupting honey bee activity
url https://doi.org/10.1371/journal.pone.0323653
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