An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa
Background: Misoprostol is a prostaglandin analogue with uterotonic properties. Administered orally or vaginally, it is an effective agent for induction of first trimester abortions. Aim: To establish the effectiveness and complications arising within the first week following the administration of...
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| Language: | English |
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AOSIS
2000-12-01
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| Series: | South African Family Practice |
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| Online Access: | https://safpj.co.za/index.php/safpj/article/view/2135 |
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| author | J. Fuchs H. de Klerk P.J.T. de Villiers C. Atzl |
| author_facet | J. Fuchs H. de Klerk P.J.T. de Villiers C. Atzl |
| author_sort | J. Fuchs |
| collection | DOAJ |
| description | Background: Misoprostol is a prostaglandin analogue with uterotonic properties. Administered orally or vaginally, it is an effective agent for induction of first trimester abortions.
Aim: To establish the effectiveness and complications arising within the first week following the administration of Misoprostol for termination of pregnancy (TOP) in the first trimester of pregnancy.
Setting: A regional hospital in the Helderberg basin of the greater Cape Town area, serving both as district and secondary hospital.
Methods: Prospective descriptive study of patients using Misoprostol as induction agent in the first trimester of pregnancy. Success rate, side effects and complications were monitored over three visits, up until one week after termination
Results: 105 patients were enrolled into the study. Following the intake of Misoprostol, 70% reported a successful induction within 48 hours. The evacuation of the uterus was found to be uncomplicated in 64% of these patients. 9% received a repeat dose of Misoprostol, 3% required a third medical induction. In 1 patient with an unsuccessful induction, an ectopic pregnancy was diagnosed. In 4 women the uterus had been surgically perforated, without need for further surgery.
Conclusion: The use of Misoprostol for the induction of termination of pregnancy in the first trimester proved to be effective and acceptably safe. |
| format | Article |
| id | doaj-art-2cc55acc7fcf433ebf9aa7d356aac4f6 |
| institution | Kabale University |
| issn | 2078-6190 2078-6204 |
| language | English |
| publishDate | 2000-12-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Family Practice |
| spelling | doaj-art-2cc55acc7fcf433ebf9aa7d356aac4f62025-08-20T04:03:17ZengAOSISSouth African Family Practice2078-61902078-62042000-12-0122710.4102/safp.v22i7.21351679An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South AfricaJ. Fuchs0H. de Klerk1P.J.T. de Villiers2C. Atzl3Stellenbosch UniversityStellenbosch UniversityStellenbosch UniversityTygerberg HospitalBackground: Misoprostol is a prostaglandin analogue with uterotonic properties. Administered orally or vaginally, it is an effective agent for induction of first trimester abortions. Aim: To establish the effectiveness and complications arising within the first week following the administration of Misoprostol for termination of pregnancy (TOP) in the first trimester of pregnancy. Setting: A regional hospital in the Helderberg basin of the greater Cape Town area, serving both as district and secondary hospital. Methods: Prospective descriptive study of patients using Misoprostol as induction agent in the first trimester of pregnancy. Success rate, side effects and complications were monitored over three visits, up until one week after termination Results: 105 patients were enrolled into the study. Following the intake of Misoprostol, 70% reported a successful induction within 48 hours. The evacuation of the uterus was found to be uncomplicated in 64% of these patients. 9% received a repeat dose of Misoprostol, 3% required a third medical induction. In 1 patient with an unsuccessful induction, an ectopic pregnancy was diagnosed. In 4 women the uterus had been surgically perforated, without need for further surgery. Conclusion: The use of Misoprostol for the induction of termination of pregnancy in the first trimester proved to be effective and acceptably safe.https://safpj.co.za/index.php/safpj/article/view/2135misoprostolabortioncomplicationsfirst trimester pregnancyhospital |
| spellingShingle | J. Fuchs H. de Klerk P.J.T. de Villiers C. Atzl An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa South African Family Practice misoprostol abortion complications first trimester pregnancy hospital |
| title | An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa |
| title_full | An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa |
| title_fullStr | An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa |
| title_full_unstemmed | An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa |
| title_short | An Experience with Misoprostol for the Induction of First Trimester Abortions in a Secondary Hospital in South Africa |
| title_sort | experience with misoprostol for the induction of first trimester abortions in a secondary hospital in south africa |
| topic | misoprostol abortion complications first trimester pregnancy hospital |
| url | https://safpj.co.za/index.php/safpj/article/view/2135 |
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