Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

Abstract Condition‐dependent genetic interactions can reveal functional relationships between genes that are not evident under standard culture conditions. State‐of‐the‐art yeast genetic interaction mapping, which relies on robotic manipulation of arrays of double‐mutant strains, does not scale read...

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Bibliographic Details
Main Authors: J Javier Díaz‐Mejía, Albi Celaj, Joseph C Mellor, Atina Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile, Marta Verby, Anna Karkhanina, YiFan Zhang, Cassandra Wong, Justin Rich, D'Arcy Prendergast, Gaurav Gupta, Sedide Öztürk, Daniel Durocher, Grant W Brown, Frederick P Roth
Format: Article
Language:English
Published: Springer Nature 2018-05-01
Series:Molecular Systems Biology
Subjects:
condition‐dependent
DNA barcode
en masse
genetic interaction
sequencing
Online Access:https://doi.org/10.15252/msb.20177985
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