Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy
Aim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therap...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2008-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1627 |
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| _version_ | 1849342367850561536 |
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| author | M. V. Lozhakova |
| author_facet | M. V. Lozhakova |
| author_sort | M. V. Lozhakova |
| collection | DOAJ |
| description | Aim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therapy (10 mg once a day), all participants underwent 24-hour blood pressure monitoring (BPM), peripheral hemodynamics and MC assessment.Results. Eight-week bisoprolol therapy (10 mg/d) was associated with target BP level achievement in 74% of the patients. In 76%, circadian BP profile had been normalized. Bisoprolol treatment also improved peripheral hemodynamics and MC parameters. Significant reduction in total peripheral vascular resistance and pulse wave velocity was observed in 95%, normalization of these parameters - in 54%. MC parameters normalized in 67% and improved in 94%.Conclusion. Bisoprolol demonstrated high antihypertensive activity and beneficial effects on peripheral hemodynamics and MC parameters. |
| format | Article |
| id | doaj-art-2cbe432d2aa84c3d85ec10d96bb6505d |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2008-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2cbe432d2aa84c3d85ec10d96bb6505d2025-08-20T03:43:26Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-12-017617201344Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapyM. V. Lozhakova0Nizhniy Novgorod State Medical Academy. Nizhniy NovgorodAim. To study eight-week bisoprolol therapy effects on peripheral hemodynamics and microcirculation (MC) parameters.Material and methods. The study included 34 patients with stage II arterial hypertension (AH): 18 men, 16 women; median age 47 years. At baseline and after 8 weeks of bisoprolol therapy (10 mg once a day), all participants underwent 24-hour blood pressure monitoring (BPM), peripheral hemodynamics and MC assessment.Results. Eight-week bisoprolol therapy (10 mg/d) was associated with target BP level achievement in 74% of the patients. In 76%, circadian BP profile had been normalized. Bisoprolol treatment also improved peripheral hemodynamics and MC parameters. Significant reduction in total peripheral vascular resistance and pulse wave velocity was observed in 95%, normalization of these parameters - in 54%. MC parameters normalized in 67% and improved in 94%.Conclusion. Bisoprolol demonstrated high antihypertensive activity and beneficial effects on peripheral hemodynamics and MC parameters.https://cardiovascular.elpub.ru/jour/article/view/1627bisoprolol24-hour blood pressure monitoringperipheral hemodynamics parametersmicrocirculation |
| spellingShingle | M. V. Lozhakova Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy Кардиоваскулярная терапия и профилактика bisoprolol 24-hour blood pressure monitoring peripheral hemodynamics parameters microcirculation |
| title | Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| title_full | Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| title_fullStr | Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| title_full_unstemmed | Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| title_short | Peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| title_sort | peripheral hemodynamics and microcirculation dynamics in arterial hypertension patients receiving bisoprolol monotherapy |
| topic | bisoprolol 24-hour blood pressure monitoring peripheral hemodynamics parameters microcirculation |
| url | https://cardiovascular.elpub.ru/jour/article/view/1627 |
| work_keys_str_mv | AT mvlozhakova peripheralhemodynamicsandmicrocirculationdynamicsinarterialhypertensionpatientsreceivingbisoprololmonotherapy |