An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report

Background: Pseudescherichia vulneris is a rare pathogen associated with infections in immunocompromised adults. This may be the first documented report of a neonate with late-onset sepsis. Case Report: An 18-day-old term baby was admitted to the pediatric unit with a five-day history of fever and...

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Main Authors: S. Mustapha, A. Musa, M. Ibrahim, M. Idris, S. Aliyu, I. Abdulkadir
Format: Article
Language:English
Published: Verduci Editore 2024-09-01
Series:Infectious Diseases and Tropical Medicine
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Online Access:https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/09/Art.-36563.pdf
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author S. Mustapha
A. Musa
M. Ibrahim
M. Idris
S. Aliyu
I. Abdulkadir
author_facet S. Mustapha
A. Musa
M. Ibrahim
M. Idris
S. Aliyu
I. Abdulkadir
author_sort S. Mustapha
collection DOAJ
description Background: Pseudescherichia vulneris is a rare pathogen associated with infections in immunocompromised adults. This may be the first documented report of a neonate with late-onset sepsis. Case Report: An 18-day-old term baby was admitted to the pediatric unit with a five-day history of fever and refusal to feed. The infant was irritable, jaundiced, and pale. Notably, the mother experienced prolonged premature rupture of membranes (PROM). Blood culture isolated multi-drug-resistant P. vulneris and Acinetobacter baumannii. Identifying the organism was challenging due to its rarity, phenotypic similarity to other Enterobacteriaceae, and limited access to advanced diagnostic tools. The treatment was successful, as the baby responded well to antibiotics and was discharged. Conclusions: This case highlights the potential for rare pathogens to cause neonatal sepsis, the challenges in diagnosing such infections in resource-limited settings, and the risk of multidrug-resistant strains emerging in the isolate. The case also underscores the necessity for further research to elucidate the pathogenesis, epidemiology, and optimal management of P. vulneris infections.
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series Infectious Diseases and Tropical Medicine
spelling doaj-art-2cb6969780484a559e23b6a2ecb7c2fa2025-08-20T03:07:31ZengVerduci EditoreInfectious Diseases and Tropical Medicine2379-40542024-09-011010.32113/idtm_20249_15391539An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case reportS. Mustapha0A. Musa1M. Ibrahim2M. Idris3S. Aliyu4I. Abdulkadir5Department of Paediatrics, Abubakar Tafawa Balewa University, Bauchi, NigeriaDepartment of Paediatrics, Abubakar Tafawa Balewa University, Bauchi, NigeriaDepartment of Medical Microbiology and Immunology, Gombe State University / Federal Teaching Hospital, Gombe, NigeriaDepartment of Medical Microbiology, Ahmadu Bello University, Teaching Hospital, Zaria, NigeriaDepartment of Medical Microbiology, Ahmadu Bello University, Zaria, NigeriaDepartment of Paediatrics, Ahmadu Bello University, Zaria, NigeriaBackground: Pseudescherichia vulneris is a rare pathogen associated with infections in immunocompromised adults. This may be the first documented report of a neonate with late-onset sepsis. Case Report: An 18-day-old term baby was admitted to the pediatric unit with a five-day history of fever and refusal to feed. The infant was irritable, jaundiced, and pale. Notably, the mother experienced prolonged premature rupture of membranes (PROM). Blood culture isolated multi-drug-resistant P. vulneris and Acinetobacter baumannii. Identifying the organism was challenging due to its rarity, phenotypic similarity to other Enterobacteriaceae, and limited access to advanced diagnostic tools. The treatment was successful, as the baby responded well to antibiotics and was discharged. Conclusions: This case highlights the potential for rare pathogens to cause neonatal sepsis, the challenges in diagnosing such infections in resource-limited settings, and the risk of multidrug-resistant strains emerging in the isolate. The case also underscores the necessity for further research to elucidate the pathogenesis, epidemiology, and optimal management of P. vulneris infections.https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/09/Art.-36563.pdfpseudescherichia vulnerisinfectionneonaterarecase report.
spellingShingle S. Mustapha
A. Musa
M. Ibrahim
M. Idris
S. Aliyu
I. Abdulkadir
An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
Infectious Diseases and Tropical Medicine
pseudescherichia vulneris
infection
neonate
rare
case report.
title An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
title_full An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
title_fullStr An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
title_full_unstemmed An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
title_short An uncommon encounter: Pseudescherichia vulneris infection in a neonate. A case report
title_sort uncommon encounter pseudescherichia vulneris infection in a neonate a case report
topic pseudescherichia vulneris
infection
neonate
rare
case report.
url https://www.infectiousjournal.com/wp-content/uploads/sites/6/2024/09/Art.-36563.pdf
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