Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities

Plant-mediated methods of synthesizing nanoparticles have piqued the fascination due to their economical, rapidity, and environmental biocompatibility. Metal/metal oxide-based nanoparticles have long been a major attraction of researchers around the globe in various applications intersecting the var...

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Main Authors: Tijo Cherian, Teena Merlin, Karthika Rajendran, Jacob Thomas
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Surfaces and Interfaces
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666845925001497
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author Tijo Cherian
Teena Merlin
Karthika Rajendran
Jacob Thomas
author_facet Tijo Cherian
Teena Merlin
Karthika Rajendran
Jacob Thomas
author_sort Tijo Cherian
collection DOAJ
description Plant-mediated methods of synthesizing nanoparticles have piqued the fascination due to their economical, rapidity, and environmental biocompatibility. Metal/metal oxide-based nanoparticles have long been a major attraction of researchers around the globe in various applications intersecting the various domains of science. The nanoparticles of silver, gold, zinc oxide, copper, copper oxide have been surveyed extensively with copious documentations of synthetic, applicative and practical insights. Selenium, as a precursor has remained largely been underexplored and under prospected. There is few research on the green synthesis of selenium nanoparticles (SeNPs) because of limitations with the process's intricacy, unpredictability, and possibility for low purity. Although green synthesis is virtuous for the environment, it can be time-consuming, location-dependent, and subject to change based on the plant source. Furthermore, the precise method and effects of each plant are not entirely understood, even though reducing agents in plant extracts can transform metal ions into nanoparticles. The current work presented a first-hand employment of aqueous fruit extracts of Morus alba in the biological synthesis of selenium nanoparticles (SeNPs). The characterization studies [UV–Vis (ultraviolet–visible), Raman spectroscopy, TEM (transmission electron microscopy), SEM (scanning electron microscopy), FTIR (Fourier transform infrared spectroscopy), zeta potential] authenticated and established the fabrication of SeNPs. The GC-MS (Gas chromatography-Mass spectrometry) analysis reported the presence of a multitude of organic compounds; well authenticated for the novel pharmaceutical candidates by molecular docking studies. The synthesized SeNPs reported promising and exceptional activities in various biological experimental evaluations. Also, the growing manufacturing of environmentally friendly nanoparticles necessitates research on their safety for biological systems and environment. The findings demonstrated that the SeNPs might, in a dose-dependent way, lower the end-points of photosensitive pigments and biomass of Chlorella vulgaris. The dye reaction dynamics was found to be outstandingly high following pseudo-first order kinetics with a 95–96 % degradation rate, implying SeNPs as favorable candidates for catalysis.
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spelling doaj-art-2cb2e72123584d27a99b9c805ac4e1e22025-08-20T02:30:19ZengElsevierResults in Surfaces and Interfaces2666-84592025-05-011910056210.1016/j.rsurfi.2025.100562Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialitiesTijo Cherian0Teena Merlin1Karthika Rajendran2Jacob Thomas3Department of Marine Biology and Ocean Studies, Pondicherry University, Port Blair Campus, Andamans, 744112, India; Corresponding author.School of Biosciences, Mar Athanasios College for Advanced Studies Tiruvalla, Tiruvalla, 689101, Kerala, IndiaSchool of Biosciences, Mar Athanasios College for Advanced Studies Tiruvalla, Tiruvalla, 689101, Kerala, IndiaDepartment of Botany, Mar Thoma College, Tiruvalla, 689103, Kerala, IndiaPlant-mediated methods of synthesizing nanoparticles have piqued the fascination due to their economical, rapidity, and environmental biocompatibility. Metal/metal oxide-based nanoparticles have long been a major attraction of researchers around the globe in various applications intersecting the various domains of science. The nanoparticles of silver, gold, zinc oxide, copper, copper oxide have been surveyed extensively with copious documentations of synthetic, applicative and practical insights. Selenium, as a precursor has remained largely been underexplored and under prospected. There is few research on the green synthesis of selenium nanoparticles (SeNPs) because of limitations with the process's intricacy, unpredictability, and possibility for low purity. Although green synthesis is virtuous for the environment, it can be time-consuming, location-dependent, and subject to change based on the plant source. Furthermore, the precise method and effects of each plant are not entirely understood, even though reducing agents in plant extracts can transform metal ions into nanoparticles. The current work presented a first-hand employment of aqueous fruit extracts of Morus alba in the biological synthesis of selenium nanoparticles (SeNPs). The characterization studies [UV–Vis (ultraviolet–visible), Raman spectroscopy, TEM (transmission electron microscopy), SEM (scanning electron microscopy), FTIR (Fourier transform infrared spectroscopy), zeta potential] authenticated and established the fabrication of SeNPs. The GC-MS (Gas chromatography-Mass spectrometry) analysis reported the presence of a multitude of organic compounds; well authenticated for the novel pharmaceutical candidates by molecular docking studies. The synthesized SeNPs reported promising and exceptional activities in various biological experimental evaluations. Also, the growing manufacturing of environmentally friendly nanoparticles necessitates research on their safety for biological systems and environment. The findings demonstrated that the SeNPs might, in a dose-dependent way, lower the end-points of photosensitive pigments and biomass of Chlorella vulgaris. The dye reaction dynamics was found to be outstandingly high following pseudo-first order kinetics with a 95–96 % degradation rate, implying SeNPs as favorable candidates for catalysis.http://www.sciencedirect.com/science/article/pii/S2666845925001497Anti-inflammatoryAnti-agingEnvironmental impact assessmentMolecular dockingMorus albaNanotechnology
spellingShingle Tijo Cherian
Teena Merlin
Karthika Rajendran
Jacob Thomas
Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
Results in Surfaces and Interfaces
Anti-inflammatory
Anti-aging
Environmental impact assessment
Molecular docking
Morus alba
Nanotechnology
title Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
title_full Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
title_fullStr Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
title_full_unstemmed Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
title_short Biogenic production and characterization of SeNPs (selenium nanoparticles) utilizing aqueous fruit extract of Morus alba and assessment of their biological potentialities
title_sort biogenic production and characterization of senps selenium nanoparticles utilizing aqueous fruit extract of morus alba and assessment of their biological potentialities
topic Anti-inflammatory
Anti-aging
Environmental impact assessment
Molecular docking
Morus alba
Nanotechnology
url http://www.sciencedirect.com/science/article/pii/S2666845925001497
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