Veratridine-Induced Oscillations in Nav 1.7 but Not Nav 1.5 Sodium Channels Are Revealed by Membrane Potential Sensitive Dye

Veratridine-Induced Oscillations in Nav 1.7 but Not Nav 1.5 Sodium Channels Are Revealed by Membrane Potential Sensitive Dye

Voltage-gated sodium channels (Navs) are critical for membrane potential depolarisation in cells, with especially important roles in neuronal and cardiomyocyte membranes. Their malfunction results in a range of disorders, and they are the target of many widely used drugs. A rapid yet accurate functi...

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Bibliographic Details
Main Authors: Sarah C. R. Lummis, Samantha C. Salvage, Christopher L.-H. Huang, Antony P. Jackson
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Membranes
Subjects:
oscillations
depolarization
Flexstation
voltage-gated sodium channel
voltage-sensitive dye
Online Access:https://www.mdpi.com/2077-0375/15/3/80
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