Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review

In the last decade, the disadvantages of coronary artery (CA) drugeluting stenting have become increasingly obvious. Metallization of the artery, loss of vasoreactivity and chronic inflammation at the implantation site lead to restenosis and an increased risk of repeated revascularization. In this r...

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Main Authors: D. K. Vasiliev, N. A. Arablinsky
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2025-07-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/4362
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author D. K. Vasiliev
N. A. Arablinsky
author_facet D. K. Vasiliev
N. A. Arablinsky
author_sort D. K. Vasiliev
collection DOAJ
description In the last decade, the disadvantages of coronary artery (CA) drugeluting stenting have become increasingly obvious. Metallization of the artery, loss of vasoreactivity and chronic inflammation at the implantation site lead to restenosis and an increased risk of repeated revascularization. In this regard, the "leaving nothing behind" concept is attracting increasing interest, which came to coronary revascularization from lower limb arterial disease strategies. The treatment methods within this concept in CA include the use of biodegradable scaffolds and drug-eluting balloons (DEB). Despite the fact that both Russian and foreign guidelines for DEB establish the role of in-stent restenosis treatment, large studies demonstrate the efficacy and safety of DEB in the treatment of de novo coronary lesions. The review systematizes the latest data on the DEB potential in the treatment of de novo native coronary lesions.
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publishDate 2025-07-01
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-2caf5827192f4c8aac2aa09c0708c5902025-08-20T03:18:37Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252025-07-0124510.15829/1728-8800-2025-43623245Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? ReviewD. K. Vasiliev0N. A. Arablinsky1National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineIn the last decade, the disadvantages of coronary artery (CA) drugeluting stenting have become increasingly obvious. Metallization of the artery, loss of vasoreactivity and chronic inflammation at the implantation site lead to restenosis and an increased risk of repeated revascularization. In this regard, the "leaving nothing behind" concept is attracting increasing interest, which came to coronary revascularization from lower limb arterial disease strategies. The treatment methods within this concept in CA include the use of biodegradable scaffolds and drug-eluting balloons (DEB). Despite the fact that both Russian and foreign guidelines for DEB establish the role of in-stent restenosis treatment, large studies demonstrate the efficacy and safety of DEB in the treatment of de novo coronary lesions. The review systematizes the latest data on the DEB potential in the treatment of de novo native coronary lesions.https://cardiovascular.elpub.ru/jour/article/view/4362percutaneous coronary interventioncoronary artery diseasedrug-eluting balloon catheterdrug-eluting balloonintravascular imaging
spellingShingle D. K. Vasiliev
N. A. Arablinsky
Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
Кардиоваскулярная терапия и профилактика
percutaneous coronary intervention
coronary artery disease
drug-eluting balloon catheter
drug-eluting balloon
intravascular imaging
title Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
title_full Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
title_fullStr Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
title_full_unstemmed Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
title_short Drug-eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries — the future we have already been in? Review
title_sort drug eluting balloon as an alternative to coronary stent in the treatment of de novo atherosclerotic lesions of native coronary arteries the future we have already been in review
topic percutaneous coronary intervention
coronary artery disease
drug-eluting balloon catheter
drug-eluting balloon
intravascular imaging
url https://cardiovascular.elpub.ru/jour/article/view/4362
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