Lues Maligna in Immunocompetent Individuals: Two Case Reports
Lues maligna, also termed malignant syphilis or rupioid syphilis, is a rare and severe form of secondary syphilis. Clinically, the condition is characterized by unusual nodules and necrotic and ulcerated skin lesions covered by thick, lamellated crusts associated with severe constitutional symp...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
2025-03-01
|
| Series: | Nepal Journal of Dermatology, Venereology & Leprology |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/NJDVL/article/view/74403 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849227485037723648 |
|---|---|
| author | Bishnu Prasad Adhikari Binamra Basnet Bidhan Neupane Ajay Kumar Surendra Sapkota Mandeep Dutta Joshi Kamala Subedi |
| author_facet | Bishnu Prasad Adhikari Binamra Basnet Bidhan Neupane Ajay Kumar Surendra Sapkota Mandeep Dutta Joshi Kamala Subedi |
| author_sort | Bishnu Prasad Adhikari |
| collection | DOAJ |
| description |
Lues maligna, also termed malignant syphilis or rupioid syphilis, is a rare and severe form of secondary syphilis. Clinically, the condition is characterized by unusual nodules and necrotic and ulcerated skin lesions covered by thick, lamellated crusts associated with severe constitutional symptoms. Most of the lues maligna cases have been observed in immunocompromised individuals, including Human Immunodeficiency Virus (HIV) co-infected patients, alcoholics, malnourished individuals, and patients with debilitating illnesses. However, immunocompetent individuals can also develop this form of illness. Herein, we present 2 cases of lues maligna in immunocompetent patients. The first case is a 38-year-old immunocompetent married female, while the second case is a 34-old married male, both presenting with multiple diffuse noduloulcerative lesions with rupioid crusts. Serological tests for syphilis were positive in both patients and a biopsy of both patients showed forms consistent with secondary syphilis.
|
| format | Article |
| id | doaj-art-2cae54fd65f541809418e51cb545efe2 |
| institution | Kabale University |
| issn | 2091-0231 2091-167X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) |
| record_format | Article |
| series | Nepal Journal of Dermatology, Venereology & Leprology |
| spelling | doaj-art-2cae54fd65f541809418e51cb545efe22025-08-23T10:03:23ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2025-03-0123110.3126/njdvl.v23i1.74403Lues Maligna in Immunocompetent Individuals: Two Case Reports Bishnu Prasad Adhikarihttps://orcid.org/0009-0005-5089-4465Binamra Basnet0Bidhan Neupane1Ajay Kumar2Surendra Sapkota3Mandeep Dutta Joshi4Kamala Subedi5Manipal College of Medical Sciences, Pokhara, NepalManipal College of Medical Sciences, Pokhara, Nepal Manipal College of Medical Sciences, Pokhara, NepalManipal College of Medical Sciences, Pokhara, NepalManipal College of Medical Sciences, Pokhara, NepalPokhara Academy of Health Sciences, Ramghat, Pokhara, Nepal Lues maligna, also termed malignant syphilis or rupioid syphilis, is a rare and severe form of secondary syphilis. Clinically, the condition is characterized by unusual nodules and necrotic and ulcerated skin lesions covered by thick, lamellated crusts associated with severe constitutional symptoms. Most of the lues maligna cases have been observed in immunocompromised individuals, including Human Immunodeficiency Virus (HIV) co-infected patients, alcoholics, malnourished individuals, and patients with debilitating illnesses. However, immunocompetent individuals can also develop this form of illness. Herein, we present 2 cases of lues maligna in immunocompetent patients. The first case is a 38-year-old immunocompetent married female, while the second case is a 34-old married male, both presenting with multiple diffuse noduloulcerative lesions with rupioid crusts. Serological tests for syphilis were positive in both patients and a biopsy of both patients showed forms consistent with secondary syphilis. https://www.nepjol.info/index.php/NJDVL/article/view/74403Fisher's criteriaHuman immunodeficiency virusMalignant syphilisRupioid syphilisUlceronodular-rupioid syphilis. |
| spellingShingle | Bishnu Prasad Adhikari Binamra Basnet Bidhan Neupane Ajay Kumar Surendra Sapkota Mandeep Dutta Joshi Kamala Subedi Lues Maligna in Immunocompetent Individuals: Two Case Reports Nepal Journal of Dermatology, Venereology & Leprology Fisher's criteria Human immunodeficiency virus Malignant syphilis Rupioid syphilis Ulceronodular-rupioid syphilis. |
| title | Lues Maligna in Immunocompetent Individuals: Two Case Reports |
| title_full | Lues Maligna in Immunocompetent Individuals: Two Case Reports |
| title_fullStr | Lues Maligna in Immunocompetent Individuals: Two Case Reports |
| title_full_unstemmed | Lues Maligna in Immunocompetent Individuals: Two Case Reports |
| title_short | Lues Maligna in Immunocompetent Individuals: Two Case Reports |
| title_sort | lues maligna in immunocompetent individuals two case reports |
| topic | Fisher's criteria Human immunodeficiency virus Malignant syphilis Rupioid syphilis Ulceronodular-rupioid syphilis. |
| url | https://www.nepjol.info/index.php/NJDVL/article/view/74403 |
| work_keys_str_mv | AT bishnuprasadadhikari luesmalignainimmunocompetentindividualstwocasereports AT binamrabasnet luesmalignainimmunocompetentindividualstwocasereports AT bidhanneupane luesmalignainimmunocompetentindividualstwocasereports AT ajaykumar luesmalignainimmunocompetentindividualstwocasereports AT surendrasapkota luesmalignainimmunocompetentindividualstwocasereports AT mandeepduttajoshi luesmalignainimmunocompetentindividualstwocasereports AT kamalasubedi luesmalignainimmunocompetentindividualstwocasereports |