A laminin-based therapy for dogs with chronic spinal cord injury: promising results of a longitudinal trial

A laminin-based therapy for dogs with chronic spinal cord injury: promising results of a longitudinal trial

IntroductionPolylaminin, an improved form of the natural protein laminin, has been shown to promote axonal regeneration and functional recovery in animal models of acute spinal cord injury (SCI), and is safe and potentially beneficial in humans when administered within the first days after traumatic...

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Bibliographic Details
Main Authors: Carolina de Miranda Chize, Diego Gonzales Vivas, Karla Menezes, Max Nascimento Freire, Rodrigo Ferreira Pinto Jiddu, Aurélio Vicente Graça-Souza, Eliel de Souza-Leite, Paulo Roberto Louzada, Tatiana Coelho-Sampaio
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Veterinary Science
Subjects:
spinal cord injury
chronic
laminin
polylaminin
chondroitinase ABC
GDNF
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1592687/full
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