A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis

A 63-year-old man was diagnosed with multiple lung metastases from anaplastic thyroid cancer and received lenvatinib. Follow-up computed tomography on day 34 of lenvatinib treatment showed pneumothorax. The pneumothorax was temporarily improved with chest drainage. However, pleurodesis was performed...

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Main Authors: Haruhiko Yamazaki, Hiroyuki Iwasaki, Toshinari Yamashita, Tatsuya Yoshida, Nobuyasu Suganuma, Takashi Yamanaka, Katsuhiko Masudo, Hirotaka Nakayama, Kaori Kohagura, Yasushi Rino, Munetaka Masuda
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2018/7875929
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author Haruhiko Yamazaki
Hiroyuki Iwasaki
Toshinari Yamashita
Tatsuya Yoshida
Nobuyasu Suganuma
Takashi Yamanaka
Katsuhiko Masudo
Hirotaka Nakayama
Kaori Kohagura
Yasushi Rino
Munetaka Masuda
author_facet Haruhiko Yamazaki
Hiroyuki Iwasaki
Toshinari Yamashita
Tatsuya Yoshida
Nobuyasu Suganuma
Takashi Yamanaka
Katsuhiko Masudo
Hirotaka Nakayama
Kaori Kohagura
Yasushi Rino
Munetaka Masuda
author_sort Haruhiko Yamazaki
collection DOAJ
description A 63-year-old man was diagnosed with multiple lung metastases from anaplastic thyroid cancer and received lenvatinib. Follow-up computed tomography on day 34 of lenvatinib treatment showed pneumothorax. The pneumothorax was temporarily improved with chest drainage. However, pleurodesis was performed to treat a relapse of the pneumothorax. Pneumothorax during chemotherapy for a malignant tumor is considered a relatively rare complication. This case is the first documentation that pneumothorax may develop during lenvatinib treatment. The possible development of pneumothorax should be considered when lenvatinib is used in patients with lung metastasis.
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institution Kabale University
issn 2090-6501
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Endocrinology
spelling doaj-art-2c900ee4e89e4b46b4c960035b97f4f92025-02-03T01:30:36ZengWileyCase Reports in Endocrinology2090-65012090-651X2018-01-01201810.1155/2018/78759297875929A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung MetastasisHaruhiko Yamazaki0Hiroyuki Iwasaki1Toshinari Yamashita2Tatsuya Yoshida3Nobuyasu Suganuma4Takashi Yamanaka5Katsuhiko Masudo6Hirotaka Nakayama7Kaori Kohagura8Yasushi Rino9Munetaka Masuda10Department of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, JapanDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, JapanDepartment of Surgery, Yokohama City University School of Medicine, Yokohama, JapanDepartment of Surgery, Yokohama City University School of Medicine, Yokohama, JapanDepartment of Surgery, Yokohama City University School of Medicine, Yokohama, JapanDepartment of Surgery, Yokohama City University School of Medicine, Yokohama, JapanA 63-year-old man was diagnosed with multiple lung metastases from anaplastic thyroid cancer and received lenvatinib. Follow-up computed tomography on day 34 of lenvatinib treatment showed pneumothorax. The pneumothorax was temporarily improved with chest drainage. However, pleurodesis was performed to treat a relapse of the pneumothorax. Pneumothorax during chemotherapy for a malignant tumor is considered a relatively rare complication. This case is the first documentation that pneumothorax may develop during lenvatinib treatment. The possible development of pneumothorax should be considered when lenvatinib is used in patients with lung metastasis.http://dx.doi.org/10.1155/2018/7875929
spellingShingle Haruhiko Yamazaki
Hiroyuki Iwasaki
Toshinari Yamashita
Tatsuya Yoshida
Nobuyasu Suganuma
Takashi Yamanaka
Katsuhiko Masudo
Hirotaka Nakayama
Kaori Kohagura
Yasushi Rino
Munetaka Masuda
A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
Case Reports in Endocrinology
title A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
title_full A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
title_fullStr A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
title_full_unstemmed A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
title_short A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
title_sort case of pneumothorax after treatment with lenvatinib for anaplastic thyroid cancer with lung metastasis
url http://dx.doi.org/10.1155/2018/7875929
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