Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats

Abstract Background and aims Alcohol-associated liver disease (ALD) with steatosis or steatohepatitis that could progress to liver cirrhosis is a common problem in chronic alcohol consumption. Pemafibrate is a novel, highly specific peroxisome proliferator-activated receptor-α (PPARα) modulator, whi...

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Bibliographic Details
Main Authors: Takashi Saito, Joseph George, Kazuaki Ozaki, Mutsumi Tsuchishima, Mikihiro Tsutsumi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01210-9
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