Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report

ABSTRACT Fungal diseases resistant to antifungal agents in animals are a growing concern, making the study of these infections crucial for early detection of antifungal resistance in both animals and humans. Aspergillosis, which affects immunocompromised humans, domestic and wild animals, birds and...

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Main Authors: R.P. Silva, M.J.S. Oliveira, M.P. Peçanha, R.H.F. Teixeira
Format: Article
Language:English
Published: Universidade Federal de Minas Gerais 2025-07-01
Series:Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352025000401305&lng=en&tlng=en
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author R.P. Silva
M.J.S. Oliveira
M.P. Peçanha
R.H.F. Teixeira
author_facet R.P. Silva
M.J.S. Oliveira
M.P. Peçanha
R.H.F. Teixeira
author_sort R.P. Silva
collection DOAJ
description ABSTRACT Fungal diseases resistant to antifungal agents in animals are a growing concern, making the study of these infections crucial for early detection of antifungal resistance in both animals and humans. Aspergillosis, which affects immunocompromised humans, domestic and wild animals, birds and even in vertebrates, is one such infection. The aim of this study was to identify the causative agent of the fungal infection and assess its antifungal resistance. Using a sterile swab, a sample was collected from the lesion in the air sacs during thes post-mortem analysis of a black-necked swan (Cygnus melancoryphus). Laboratory test revealed the presence of the fungus Aspergillus fumigatus and the genus Penicillium spp. To evaluateantifungal resistance, a susceptibility test was performed using the disk diffusion method with application of four antifungals: itraconazole 10 μg , nystatin 100 IU, fluconazole 25 μg, and ketoconazole 50 μg. It was found that the fungi were resistant to the antifungals used in the study. This study is important for better therapy using antifungal drugs in patients with clinical signs or suspected fungal disease.
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publishDate 2025-07-01
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series Arquivo Brasileiro de Medicina Veterinária e Zootecnia
spelling doaj-art-2c8d03aa96b642908c961f346225caac2025-08-20T03:25:22ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622025-07-0177410.1590/1678-4162-13343Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case reportR.P. Silvahttps://orcid.org/0009-0009-4468-2107M.J.S. Oliveirahttps://orcid.org/0000-0002-9517-8607M.P. Peçanhahttps://orcid.org/0000-0001-5791-7176R.H.F. Teixeirahttps://orcid.org/0000-0001-8219-0845ABSTRACT Fungal diseases resistant to antifungal agents in animals are a growing concern, making the study of these infections crucial for early detection of antifungal resistance in both animals and humans. Aspergillosis, which affects immunocompromised humans, domestic and wild animals, birds and even in vertebrates, is one such infection. The aim of this study was to identify the causative agent of the fungal infection and assess its antifungal resistance. Using a sterile swab, a sample was collected from the lesion in the air sacs during thes post-mortem analysis of a black-necked swan (Cygnus melancoryphus). Laboratory test revealed the presence of the fungus Aspergillus fumigatus and the genus Penicillium spp. To evaluateantifungal resistance, a susceptibility test was performed using the disk diffusion method with application of four antifungals: itraconazole 10 μg , nystatin 100 IU, fluconazole 25 μg, and ketoconazole 50 μg. It was found that the fungi were resistant to the antifungals used in the study. This study is important for better therapy using antifungal drugs in patients with clinical signs or suspected fungal disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352025000401305&lng=en&tlng=enantifungal resistancewild birdfunguspublic health
spellingShingle R.P. Silva
M.J.S. Oliveira
M.P. Peçanha
R.H.F. Teixeira
Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
antifungal resistance
wild bird
fungus
public health
title Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
title_full Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
title_fullStr Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
title_full_unstemmed Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
title_short Coinfection with Aspergillus fumigatus and Penicillium spp. in black-necked swan (Cygnus melancoryphus) kept under human care - case report
title_sort coinfection with aspergillus fumigatus and penicillium spp in black necked swan cygnus melancoryphus kept under human care case report
topic antifungal resistance
wild bird
fungus
public health
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352025000401305&lng=en&tlng=en
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