The Mechanism of Protective Action of Plant-Derived Squalane (2,6,10,15,19,23-Hexamethyltetracosane) Against UVA Radiation-Induced Apoptosis in Human Dermal Fibroblasts

The Mechanism of Protective Action of Plant-Derived Squalane (2,6,10,15,19,23-Hexamethyltetracosane) Against UVA Radiation-Induced Apoptosis in Human Dermal Fibroblasts

Ultraviolet A (UVA) radiation has been identified as a significant factor contributing to skin photoaging and skin diseases, operating through the excessive generation of reactive oxygen species (ROS) and the subsequent induction of DNA damage. Plant-derived antioxidants have demonstrated efficacy i...

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Bibliographic Details
Main Authors: Katarzyna Wolosik, Magda Chalecka, Gabriela Gasiewska, Jerzy Palka, Arkadiusz Surazynski
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antioxidants
Subjects:
squalane
UVA radiation
oxidative stress
DNA damage
ROS
apoptosis
Online Access:https://www.mdpi.com/2076-3921/14/7/853
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