Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only
Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathologica...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2011/962518 |
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| author | Jan J. Jobsen Lambert Naudin ten Cate Marnix L. M. Lybeert Astrid Scholten Elzbieta M. van der Steen-Banasik Job van der Palen Marika C. Stenfert Kroese Annerie Slot Eltjo M. J. Schutter Sabine Siesling |
| author_facet | Jan J. Jobsen Lambert Naudin ten Cate Marnix L. M. Lybeert Astrid Scholten Elzbieta M. van der Steen-Banasik Job van der Palen Marika C. Stenfert Kroese Annerie Slot Eltjo M. J. Schutter Sabine Siesling |
| author_sort | Jan J. Jobsen |
| collection | DOAJ |
| description | Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma.
Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P=.0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P=.3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa. |
| format | Article |
| id | doaj-art-2c877f47e5d943dcaff0a2e37509735d |
| institution | DOAJ |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-2c877f47e5d943dcaff0a2e37509735d2025-08-20T03:20:25ZengWileyObstetrics and Gynecology International1687-95891687-95972011-01-01201110.1155/2011/962518962518Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement OnlyJan J. Jobsen0Lambert Naudin ten Cate1Marnix L. M. Lybeert2Astrid Scholten3Elzbieta M. van der Steen-Banasik4Job van der Palen5Marika C. Stenfert Kroese6Annerie Slot7Eltjo M. J. Schutter8Sabine Siesling9Department of Radiation Oncology, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER Enschede, The NetherlandsLaboratorium Pathologie Oost Nederland, 7512 ER Enschede, The NetherlandsDepartment of Radiation Oncology, Catharina Hospital, Eindhoven, The NetherlandsDepartment of Clinical Oncology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsArnhem Radiotherapeutic Institute, Arnhem, The NetherlandsDepartment of Research Methodology, Measurement, and Data Analysis, Faculty of Behavioral Science, University of Twente, 7500 AE Enschede, The NetherlandsRadiotherapy Institute Steden en Omstreken, Deventer, The NetherlandsRadiotherapy Institute Friesland, Leeuwarden, The NetherlandsDepartment of Obstetrics and Gynaecology, Medisch Spectrum Twente, 7513 ER Enschede, The NetherlandsComprehensive Cancer Centre North East, Enschede/Groningen, The NetherlandsObjective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P=.0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P=.3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.http://dx.doi.org/10.1155/2011/962518 |
| spellingShingle | Jan J. Jobsen Lambert Naudin ten Cate Marnix L. M. Lybeert Astrid Scholten Elzbieta M. van der Steen-Banasik Job van der Palen Marika C. Stenfert Kroese Annerie Slot Eltjo M. J. Schutter Sabine Siesling Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only Obstetrics and Gynecology International |
| title | Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only |
| title_full | Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only |
| title_fullStr | Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only |
| title_full_unstemmed | Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only |
| title_short | Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only |
| title_sort | outcome of endometrial cancer stage iiia with adnexa or serosal involvement only |
| url | http://dx.doi.org/10.1155/2011/962518 |
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