Remodeling of mitochondrial supercomplex-associated proteins in murine heart failure: implications for pyruvate and alpha-ketoglutarate metabolism

Remodeling of mitochondrial supercomplex-associated proteins in murine heart failure: implications for pyruvate and alpha-ketoglutarate metabolism

Saved in:

Bibliographic Details
Main Authors:	Claire Fong-McMaster, Stephanie Myers, Serena M. Pulente, Arsalan Haqqani, Erin E. Mulvihill, Mary-Ellen Harper
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Series:	Journal of Molecular and Cellular Cardiology Plus
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772976125001485
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Harnessing Metformin for Targeted Intervention: Addressing Cardiac Fibrosis in Plasminogen Activator Inhibitor-1 (PAI-1) Deficiency
by: Serena Pulente, et al.
Published: (2025-06-01)

Supercomplexity: bridging the gap between aesthetics and cognition
by: Alessandro Bortolotti, et al.
Published: (2025-07-01)

The association of mitochondrial morphology and supercomplex redistribution with skeletal muscle oxidative capacity in older adults
by: Mauricio Castro Sepulveda, et al.
Published: (2025-05-01)

Effects of Long-Term Cultivation on Medium with Alpha-Ketoglutarate Supplementation on Metabolic Processes of Saccharomyces cerevisiae
by: Nadia Burdyliuk, et al.
Published: (2017-01-01)

Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex
by: Katie Morris, et al.
Published: (2024-11-01)

Cholangiocarcinoma PDHA1 succinylation suppresses macrophage antigen presentation via alpha-ketoglutaric acid accumulation
by: Ning Zhang, et al.
Published: (2025-04-01)

Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart
by: Rohini Dhat, et al.
Published: (2023-04-01)

Glucose-activated JMJD1A drives visceral adipogenesis via α-ketoglutarate-dependent chromatin remodeling
by: Chenxu Yang, et al.
Published: (2025-08-01)

Streptozotocin-Induced Adaptive Modification of Mitochondrial Supercomplexes in Liver of Wistar Rats and the Protective Effect of Moringa oleifera Lam
by: María Alejandra Sánchez-Muñoz, et al.
Published: (2018-01-01)

Effects of Alpha-Ketoglutarate Supplementation on Growth Performance, Diarrhea Incidence, Plasma Amino Acid, and Nutrient Digestibility in Weaned Piglets
by: Weiyan Sun, et al.
Published: (2025-06-01)

Microgliosis, neuronal death, minor behavioral abnormalities and reduced endurance performance in alpha-ketoglutarate dehydrogenase complex deficient mice
by: Márton Kokas, et al.
Published: (2025-09-01)

Alpha-ketoglutarate promotes anxiety, activates autophagy, and suppresses antioxidant enzymes in the cerebral cortex of female mice on cafeteria diet
by: Oleh Demianchuk, et al.
Published: (2025-03-01)

A Native LH1–RC–HiPIP Supercomplex from an Extremophilic Phototroph
by: Kazutoshi Tani, et al.
Published: (2025-01-01)

Repurposing FDA-approved drugs to find a novel inhibitor of alpha-ketoglutarate-dependent dioxygenase FTO to treat esophageal cancer
by: Zeinab Mohammadi, et al.
Published: (2025-05-01)

Recruitment evaluation of a gerotherapeutic randomized controlled trial testing alpha-ketoglutarate in biologically older, middle-aged adults (ABLE)
by: Zhi Meng Lim, et al.
Published: (2025-10-01)

The Regulatory Role of α-Ketoglutarate Metabolism in Macrophages
by: Shaojuan Liu, et al.
Published: (2021-01-01)

The addition of alpha-ketoglutarate to NT-proBNP improves the prediction of long-term all-cause mortality in acute heart failure patients
by: Tianyu Xu, et al.
Published: (2025-12-01)

Addition of Sodium Pyruvate to Stored Red Blood Cells Attenuates Liver Injury in a Murine Transfusion Model
by: Sha Xia, et al.
Published: (2016-01-01)

Structure of a photosystem II-FCPII supercomplex from a haptophyte reveals a distinct antenna organization
by: Romain La Rocca, et al.
Published: (2025-05-01)

Structural basis for molecular assembly of fucoxanthin chlorophyll a/c-binding proteins in a diatom photosystem I supercomplex
by: Koji Kato, et al.
Published: (2024-10-01)

Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis
by: Jiamin Zhao, et al.
Published: (2025-07-01)

The physiological function of α-ketoglutarate acid and its research advances in stomatology
by: CHENG Chunan, et al.
Published: (2024-06-01)

Sustainable synthesis of α-ketoglutaric and methanetriacetic acids from biomass feedstocks
by: Cheng-Bin Hong, et al.
Published: (2025-02-01)

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis
by: Louise Nuyttens, et al.
Published: (2025-08-01)

Advances in the Development of Mitochondrial Pyruvate Carrier Inhibitors for Therapeutic Applications
by: Henry Politte, et al.
Published: (2025-02-01)

Targeted Redox Regulation α-Ketoglutarate Dehydrogenase Complex for the Treatment of Human Diseases
by: Ryan J. Mailloux
Published: (2025-04-01)

Essential role of the metabolite α-ketoglutarate in bone tissue and bone-related diseases
by: Wu Zuping, et al.
Published: (2025-02-01)

Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson’s disease models
by: Ge Gao, et al.
Published: (2025-02-01)

Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate.
by: Alejandro San Martín, et al.
Published: (2014-01-01)

The Inclusive Practices Tools: Trying to Take a Short Cut to Inclusion?
by: Christopher McMaster
Published: (2013-10-01)

Not All Dead White Men: Classics and Misogyny in the Digital Age
by: Aven McMaster
Published: (2020-11-01)

Regulation of α-Ketoglutarate levels by Myc affects metabolism and demethylation in porcine early embryos
by: Ran Ding, et al.
Published: (2024-11-01)

CLINICAL PATHOPHYSIOLOGY OF PYRUVATE KINASE DEFICIENCY
by: Павел Павлович Поляков, et al.
Published: (2025-03-01)

Murine Osteoblast and Osteoclast Co-culture on Demineralized Bone Paper for Bone Remodeling
by: Seema Amin, et al.
Published: (2025-06-01)

Multi-parametric quantitative evaluation of murine cervical remodeling during pregnancy and postpartum
by: Yan Yan, et al.
Published: (2025-05-01)

Lactylation of Mitochondrial Adenosine Triphosphate Synthase Subunit Alpha Regulates Vascular Remodeling and Progression of Aortic Dissection
by: Tao Yu, et al.
Published: (2025-01-01)

Immunomodulatory effects of alpha vs beta radiopharmaceutical therapy in murine prostate cancer
by: Carolina A. Ferreira, et al.
Published: (2025-05-01)

Exogenous interferon-alpha and interferon-gamma increase lethality of murine inhalational anthrax.
by: Jeffrey A Gold, et al.
Published: (2007-08-01)

Mitochondrial Encephalomyopathy Associated with Pyruvate Dehydrogenase Complex Deficiency: Eight Clinical Cases
by: Ekaterina A. Nikolaeva, et al.
Published: (2021-03-01)

Structure of human mitochondrial pyruvate carrier MPC1 and MPC2 complex
by: Yingyuan Sun, et al.
Published: (2025-07-01)