Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base
Avocado oil (AVO) is a natural source of many unsaturated fatty acids that can help protect the skin from harmful UV radiation. The high content of unsaturated fatty acids in avocado oil can affect product stability. One way to overcome the stability of avocado oil for topical preparation is by form...
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Universitas Sebelas Maret
2025-06-01
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| Series: | JPSCR: Journal of Pharmaceutical Science and Clinical Research |
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| Online Access: | https://jurnal.uns.ac.id/jpscr/article/view/100041 |
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| author | Ayu Shabrina Diva Ma'arif Pangestu Siska Amaliyah Malinda Prihantini Junvidya Heroweti Listyana Dewi Prastiwi |
| author_facet | Ayu Shabrina Diva Ma'arif Pangestu Siska Amaliyah Malinda Prihantini Junvidya Heroweti Listyana Dewi Prastiwi |
| author_sort | Ayu Shabrina |
| collection | DOAJ |
| description | Avocado oil (AVO) is a natural source of many unsaturated fatty acids that can help protect the skin from harmful UV radiation. The high content of unsaturated fatty acids in avocado oil can affect product stability. One way to overcome the stability of avocado oil for topical preparation is by formulating it into a gel base using Carbopol 980. The purpose of this study was to determine the physical stability and SPF value of avocado oil nano-emulgel (NE) with variations of Carbopol 980 as a gel base for 28 days of storage. AVONE was made with 5% AVO and Carbopol 980 base variation of 0.5% (NE1), 1.0% (NE2;), and 1.5% (NE3.) AVONE was stored in a climatic chamber at 30° ± 2°C with RH 65% ± 5%. The samples were tested for physical and SPF values before storage on days 7, 14, 21, and 28. The data obtained were analyzed statistically using one-way Anova. The AVONE on organoleptic parameters were stable; the resulting colour is broken-white with a distinctive oil aroma and thick and homogeneous texture. The pH value ranged from 6.21 ± 0.02 - 7.21 ± 0.02, with all formulas stable during storage. The viscosity value ranged from 13.28±0.23 - 47.22±0.89 dPa.s; the viscosity of NE3 was stable during storage. Adhesion and spreadability showed good ability to adhere to the skin. The SPF values ranged from 8.95±0.43 – 22.41±0.21, and NE3 was stable during storage. Avocado oil nano-emulgel with Carbopol 980 concentration of 1.5% was stable during storage. |
| format | Article |
| id | doaj-art-2c8508ebf6b54ff6ada8a8b25da2ffcb |
| institution | Kabale University |
| issn | 2503-331X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Universitas Sebelas Maret |
| record_format | Article |
| series | JPSCR: Journal of Pharmaceutical Science and Clinical Research |
| spelling | doaj-art-2c8508ebf6b54ff6ada8a8b25da2ffcb2025-08-20T03:33:38ZengUniversitas Sebelas MaretJPSCR: Journal of Pharmaceutical Science and Clinical Research2503-331X2025-06-0110111412910.20961/jpscr.v10i1.10004146155Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel BaseAyu Shabrina0Diva Ma'arif Pangestu1Siska Amaliyah2Malinda Prihantini3Junvidya Heroweti4Listyana Dewi Prastiwi5Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Wahid Hasyim, Semarang, IndonesiaFaculty of Pharmacy, Universitas Wahid Hasyim, Semarang, IndonesiaFaculty of Pharmacy, Universitas Wahid Hasyim, Semarang, IndonesiaDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Wahid Hasyim, Semarang, IndonesiaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Wahid Hasyim, Semarang, IndonesiaFaculty of Pharmacy, Universitas Muhammadiyah Kalimantan Timur, Samarinda, IndonesiaAvocado oil (AVO) is a natural source of many unsaturated fatty acids that can help protect the skin from harmful UV radiation. The high content of unsaturated fatty acids in avocado oil can affect product stability. One way to overcome the stability of avocado oil for topical preparation is by formulating it into a gel base using Carbopol 980. The purpose of this study was to determine the physical stability and SPF value of avocado oil nano-emulgel (NE) with variations of Carbopol 980 as a gel base for 28 days of storage. AVONE was made with 5% AVO and Carbopol 980 base variation of 0.5% (NE1), 1.0% (NE2;), and 1.5% (NE3.) AVONE was stored in a climatic chamber at 30° ± 2°C with RH 65% ± 5%. The samples were tested for physical and SPF values before storage on days 7, 14, 21, and 28. The data obtained were analyzed statistically using one-way Anova. The AVONE on organoleptic parameters were stable; the resulting colour is broken-white with a distinctive oil aroma and thick and homogeneous texture. The pH value ranged from 6.21 ± 0.02 - 7.21 ± 0.02, with all formulas stable during storage. The viscosity value ranged from 13.28±0.23 - 47.22±0.89 dPa.s; the viscosity of NE3 was stable during storage. Adhesion and spreadability showed good ability to adhere to the skin. The SPF values ranged from 8.95±0.43 – 22.41±0.21, and NE3 was stable during storage. Avocado oil nano-emulgel with Carbopol 980 concentration of 1.5% was stable during storage.https://jurnal.uns.ac.id/jpscr/article/view/100041avocado oilcarbopolemulgelnano-emulgelstability |
| spellingShingle | Ayu Shabrina Diva Ma'arif Pangestu Siska Amaliyah Malinda Prihantini Junvidya Heroweti Listyana Dewi Prastiwi Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base JPSCR: Journal of Pharmaceutical Science and Clinical Research avocado oil carbopol emulgel nano-emulgel stability |
| title | Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base |
| title_full | Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base |
| title_fullStr | Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base |
| title_full_unstemmed | Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base |
| title_short | Physical and SPF Value Stability Studies Avocado Oil Nano-emulgel with Carbopol 980 as A Gel Base |
| title_sort | physical and spf value stability studies avocado oil nano emulgel with carbopol 980 as a gel base |
| topic | avocado oil carbopol emulgel nano-emulgel stability |
| url | https://jurnal.uns.ac.id/jpscr/article/view/100041 |
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