The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis
The mevalonate pathway plays an important role in breast cancer and other tumor types. However, many issues remain obscure as yet regarding its mechanism of regulation and action. In the present study, we report that the expression of mevalonate pathway enzymes is mediated by the RHO guanosine nucle...
Saved in:
| Main Authors: | Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Molecular Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/1878-0261.13716 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
SREBP-2 promotes cancer progression through the mevalonate-Akt pathway in non-small cell lung cancer
by: Wenjie You, et al.
Published: (2025-07-01) -
Rho-GTPases subfamily: cellular defectors orchestrating viral infection
by: Beibei Zhang, et al.
Published: (2025-05-01) -
NEK2 Phosphorylates RhoGDI1 to Promote Cell Proliferation, Migration and Invasion Through the Activation of RhoA and Rac1 in Colon Cancer Cells
by: Jeewon Lim, et al.
Published: (2024-12-01) -
Overcoming Therapy Resistance in Colorectal Cancer: Targeting the Rac1 Signaling Pathway as a Potential Therapeutic Approach
by: Luciano E. Anselmino, et al.
Published: (2024-10-01) -
Novel polymorphism at ARHGAP24 gene and its association with growth traits in Hu sheep
by: Huili Shan, et al.
Published: (2025-12-01)