Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine

Purpose To evaluate the efficacy of antibiotic prophylaxis and determine the risk factors of infectious complications after transurethral surgery of the prostate. Materials and Methods Seven hundred and seventy-two patients who underwent transurethral resection of the prostate (TURP) or holmium lase...

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Main Authors: Seong Hyeon Yu, Seung Il Jung, Eu Chang Hwang, Tae-Hyoung Kim, Jae Duck Choi, Koo Han Yoo, Jeong Woo Lee, Dong Hoon Koh, Sangrak Bae, Seung Ok Yang, Joongwon Choi, Seung Ki Min, Hoon Choi
Format: Article
Language:English
Published: Korean Association of Urogenital Tract Infection and Inflammation 2022-12-01
Series:Urogenital Tract Infection
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Online Access:http://euti.org/upload/pdf/uti-17-3-81.pdf
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author Seong Hyeon Yu
Seung Il Jung
Eu Chang Hwang
Tae-Hyoung Kim
Jae Duck Choi
Koo Han Yoo
Jeong Woo Lee
Dong Hoon Koh
Sangrak Bae
Seung Ok Yang
Joongwon Choi
Seung Ki Min
Hoon Choi
author_facet Seong Hyeon Yu
Seung Il Jung
Eu Chang Hwang
Tae-Hyoung Kim
Jae Duck Choi
Koo Han Yoo
Jeong Woo Lee
Dong Hoon Koh
Sangrak Bae
Seung Ok Yang
Joongwon Choi
Seung Ki Min
Hoon Choi
author_sort Seong Hyeon Yu
collection DOAJ
description Purpose To evaluate the efficacy of antibiotic prophylaxis and determine the risk factors of infectious complications after transurethral surgery of the prostate. Materials and Methods Seven hundred and seventy-two patients who underwent transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HOLEP) were reviewed. Of these, this study enrolled 643 patients without bacteriuria who had not received antibiotics for urinary tract infections for two weeks before surgery. The patients were divided into two groups according to the duration of the antibiotics (Group 1: less than one day, n=396 vs. Group 2: more than one day, n=247). Results The overall incidence of postoperative infectious complications in 643 patients was 5.0% (32/643). When postoperative infectious complications were compared according to the duration of the antibiotics (Group 1 vs. Group 2), the infectious complications rates were 5.6% (22/396) vs. 4.0% (10/247), respectively (p=0.393). When postoperative infectious complications were compared according to the duration of antibiotics (Group 1 vs. Group 2) in the TURP and HOLEP groups, the infectious complications rates were 6.3% (12/192) vs. 1.0% (1/103) (p=0.035) and 4.9% (10/203) vs. 6.0% (8/134) (p=0.677), respectively. The duration of Foley catheterization was independently associated with infectious complications (p=0.003). Conclusions The results showed that prolonged postoperative catheterization affects postoperative infectious complications associated with transurethral prostate surgery. Although antibiotics administered for less than one day are effective for antibiotic prophylaxis of transurethral prostate surgery, a longer antibiotic therapy is recommended for TURP.
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publishDate 2022-12-01
publisher Korean Association of Urogenital Tract Infection and Inflammation
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spelling doaj-art-2c77147f9a98411a9dd702e3c9d377922025-08-20T03:32:07ZengKorean Association of Urogenital Tract Infection and InflammationUrogenital Tract Infection2465-82432465-85102022-12-01173818810.14777/uti.2022.17.3.81388Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile UrineSeong Hyeon Yu0Seung Il Jung1Eu Chang Hwang2Tae-Hyoung Kim3Jae Duck Choi4Koo Han Yoo5Jeong Woo Lee6Dong Hoon Koh7Sangrak Bae8Seung Ok Yang9Joongwon Choi10Seung Ki Min11Hoon Choi12Department of Urology, Chonnam National University Medical School, Gwangju, Department of Urology, Chonnam National University Medical School, Gwangju, Department of Urology, Chonnam National University Medical School, Gwangju, Department of Urology, Chung-Ang University College of Medicine, Seoul, Department of Urology, Nowon Eulji Medical Center, Eulji University, Seoul, Department of Urology, College of Medicine, Kyung Hee University, Seoul, Department of Urology, College of Medicine, Kyung Hee University, Seoul, Department of Urology, College of Medicine, Konyang University, Daejeon, Department of Urology, The Catholic University of Korea, Uijeongbu St. Maryʼs Hospital, Seoul, Department of Urology, Veterans Health Service Medical Center, Seoul, Department of Urology, The Catholic University of Korea, Incheon St. MaryDepartment of Urology, Goldman Urologic Clinic, Seoul, Department of Urology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, KoreaPurpose To evaluate the efficacy of antibiotic prophylaxis and determine the risk factors of infectious complications after transurethral surgery of the prostate. Materials and Methods Seven hundred and seventy-two patients who underwent transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HOLEP) were reviewed. Of these, this study enrolled 643 patients without bacteriuria who had not received antibiotics for urinary tract infections for two weeks before surgery. The patients were divided into two groups according to the duration of the antibiotics (Group 1: less than one day, n=396 vs. Group 2: more than one day, n=247). Results The overall incidence of postoperative infectious complications in 643 patients was 5.0% (32/643). When postoperative infectious complications were compared according to the duration of the antibiotics (Group 1 vs. Group 2), the infectious complications rates were 5.6% (22/396) vs. 4.0% (10/247), respectively (p=0.393). When postoperative infectious complications were compared according to the duration of antibiotics (Group 1 vs. Group 2) in the TURP and HOLEP groups, the infectious complications rates were 6.3% (12/192) vs. 1.0% (1/103) (p=0.035) and 4.9% (10/203) vs. 6.0% (8/134) (p=0.677), respectively. The duration of Foley catheterization was independently associated with infectious complications (p=0.003). Conclusions The results showed that prolonged postoperative catheterization affects postoperative infectious complications associated with transurethral prostate surgery. Although antibiotics administered for less than one day are effective for antibiotic prophylaxis of transurethral prostate surgery, a longer antibiotic therapy is recommended for TURP.http://euti.org/upload/pdf/uti-17-3-81.pdfurinary tract infectionstransurethral resection of prostaterisk factorsantibiotic prophylaxis
spellingShingle Seong Hyeon Yu
Seung Il Jung
Eu Chang Hwang
Tae-Hyoung Kim
Jae Duck Choi
Koo Han Yoo
Jeong Woo Lee
Dong Hoon Koh
Sangrak Bae
Seung Ok Yang
Joongwon Choi
Seung Ki Min
Hoon Choi
Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
Urogenital Tract Infection
urinary tract infections
transurethral resection of prostate
risk factors
antibiotic prophylaxis
title Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
title_full Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
title_fullStr Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
title_full_unstemmed Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
title_short Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
title_sort korean multicenter study of infectious complications after transurethral prostate surgery in patients with preoperative sterile urine
topic urinary tract infections
transurethral resection of prostate
risk factors
antibiotic prophylaxis
url http://euti.org/upload/pdf/uti-17-3-81.pdf
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