Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile
Aims and Method. The present study examined the relationship between the metabolic risk profile (MRP) and total testosterone (TT) and free testosterone using the free androgen index (FAI) and sex hormone binding globulin (SHBG) in 36 Caucasian American (CA) and 30 African-American (AA) women volunte...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2010/174652 |
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| _version_ | 1849693421906690048 |
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| author | Arlette Perry Xuewen Wang Ronald Goldberg Robert Ross Loreto Jackson |
| author_facet | Arlette Perry Xuewen Wang Ronald Goldberg Robert Ross Loreto Jackson |
| author_sort | Arlette Perry |
| collection | DOAJ |
| description | Aims and Method. The present study examined the relationship between the metabolic risk profile (MRP) and total testosterone (TT) and free testosterone using the free androgen index (FAI) and sex hormone binding globulin (SHBG) in 36 Caucasian American (CA) and 30 African-American (AA) women volunteering for a weight loss study.
Results. After controlling for age, significant relationships were found between TT and diastolic blood pressure (P=.004 and P=.015 in CA and AA women, resp.). Additionally, total cholesterol (P=.003), low density lipoprotein cholesterol (P=.004), apolipoprotein B (P=.006), and the total cholesterol/high density lipoprotein cholesterol (P=.027) were significantly related to TT in AA women only.
In CA women, similar measures of glucose/insulin status related to FAI, were also related to SHBG. In both CA and AA women, SHBG was related to waist (P=.031 and P=.022 resp.).
Conclusion. Our findings showed racial disparities in the relationship between the sex steroid milieu and the MRP in overweight/obese CA and AA women. |
| format | Article |
| id | doaj-art-2c732aec52c64bffb6dc794efeef0735 |
| institution | DOAJ |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-2c732aec52c64bffb6dc794efeef07352025-08-20T03:20:25ZengWileyJournal of Obesity2090-07082090-07162010-01-01201010.1155/2010/174652174652Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk ProfileArlette Perry0Xuewen Wang1Ronald Goldberg2Robert Ross3Loreto Jackson4Laboratory of Clinical and Applied Physiology, University of Miami, P.O. Box 248065, Coral Gables, FL 33124, USADivision of Geriatrics and Nutritional Science, Washington University School of Medicine, 660 S. Euclid Avenue, Louis street, MO 63110, USADiabetes Research Institute, Miller School of Medicine, University of Miami, 1450 NW 10th Avenue, Miami, FL 33136, USADepartment of Medicine, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, K7L 3N6, CanadaClemson University, Clemson, SC 29634, USAAims and Method. The present study examined the relationship between the metabolic risk profile (MRP) and total testosterone (TT) and free testosterone using the free androgen index (FAI) and sex hormone binding globulin (SHBG) in 36 Caucasian American (CA) and 30 African-American (AA) women volunteering for a weight loss study. Results. After controlling for age, significant relationships were found between TT and diastolic blood pressure (P=.004 and P=.015 in CA and AA women, resp.). Additionally, total cholesterol (P=.003), low density lipoprotein cholesterol (P=.004), apolipoprotein B (P=.006), and the total cholesterol/high density lipoprotein cholesterol (P=.027) were significantly related to TT in AA women only. In CA women, similar measures of glucose/insulin status related to FAI, were also related to SHBG. In both CA and AA women, SHBG was related to waist (P=.031 and P=.022 resp.). Conclusion. Our findings showed racial disparities in the relationship between the sex steroid milieu and the MRP in overweight/obese CA and AA women.http://dx.doi.org/10.1155/2010/174652 |
| spellingShingle | Arlette Perry Xuewen Wang Ronald Goldberg Robert Ross Loreto Jackson Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile Journal of Obesity |
| title | Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile |
| title_full | Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile |
| title_fullStr | Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile |
| title_full_unstemmed | Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile |
| title_short | Racial Disparities between the Sex Steroid Milieu and the Metabolic Risk Profile |
| title_sort | racial disparities between the sex steroid milieu and the metabolic risk profile |
| url | http://dx.doi.org/10.1155/2010/174652 |
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