Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma

Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma

Abstract Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Consensus clustering and non-negative matrix...

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Bibliographic Details
Main Authors: Guoyin Li, Yukui Zhao, Yubo He, Zhaoqiang Qian, Yiwen Liu, Xiaoyan Li, Lili Li, Zhiqiang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Glioma
Immunogenic cell death
Prognostic model
SERPINH1
JAK/STAT pathway
Online Access:https://doi.org/10.1038/s41598-025-15658-6
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