Notch and Hedgehog Signalling Axis Drive Senescence in HER2-Positive Breast Cancer Resistant to Trastuzumab
Objective: Cellular senescence halts the proliferation of damaged or preneoplastic cells, playing a vital role in cancer control. In HER2-positive breast cancer, resistance to trastuzumab, a HER2-targeted monoclonal antibody, remains a significant obstacle. Although the trastuzumab and cilengitide c...
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| Main Authors: | Asiye Büşra Boz Er, İdris Er |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2024-12-01
|
| Series: | European Journal of Biology |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/D7F3CFA6B9DA4A0CA8E0D9DF84153C26 |
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