Decreased nitric oxide levels in the hippocampus may play a role in learning and memory deficits in ovariectomized rats treated by a high dose of estradiol

The effects of a high estradiol dose on memory and on nitric oxide metabolites in hippocampal tissues were investigated. Sham-Est and OVX-Est Groups were treated with 4 mg/kg of estradiol valerate for 12 weeks. Time latency and path length were significantly higher in the Sham-Est and OVX-Est Groups...

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Bibliographic Details
Main Authors: Reihaneh Sadeghian, Masoud Fereidoni, Mohammad Soukhtanloo, Hamid Azizi-Malekabadi, Mahmoud Hosseini
Format: Article
Language:English
Published: Thieme Revinter Publicações 2012-11-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001100010&lng=en&tlng=en
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